BMJ Open Diabetes Research & Care is a high-quality source for basic and clinical research regarding type 1 and type 2 diabetes, and associated complications. A rapid review process — and continuous online updates — ensure the publication of timely research.
Published by BMJ in partnership with the American Diabetes Association.
Coxsackie–adenovirus receptor expression is enhanced in pancreas from patients with type 1 diabetes
One of the theories connecting enterovirus (EV) infection of human islets with type 1 diabetes (T1D) is the development of
a fertile field in the islets. This implies induction of appropriate proteins for the viral replication such as the coxsackie–adenovirus
receptor (CAR). The aim of this study was to investigate to what extent CAR is expressed in human islets of Langerhans, and
what conditions that would change the expression.
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