Table 3

Pain and neuropathic pain measures from baseline to final visit with significance at each visit

Pain and neuropathy measuresPretreatment baselineV2V3V4V5
Total McGill pain location
Median (IQR) (−/45)
21.3±15.0
23 (7–36)
19.1±15.9
13 (5–36)
7.5±7.5*
5 (2–11)*
6.5±6.4*
5 (2–9)*
5.9±5.3*
5 (3–8)*
McGill pain score (−/5)2.1±0.91.9±1.01.7±1.1ª1.5±1.0*1.5±1.0*
DN4
Median (IQR) (−/10)
3.0±1.8
3 (2–4)
2.8±2.1
3 (1–4)
2.6±1.9
2 (1–4)
2.8±2.1
3 (1–4)
2.8±2.1
3 (1–4)
Positive symptoms (DN4)
Median (IQR) (−/6)
2.0±1.4
2 (1–3)
1.7±1.5
1 (1–3)
1.5±1.4#
1 (0–2)
1.4±1.4^
1 (0–2)
1.4±1.2**
1 (0–2)
  • *p<0.0001, ªp=0.007, #p=0.03, ^p=0.006, **p=0.004.

  • DN4, Douleur Neuropathique 4; V2, visit 2.