Characteristics of individuals included
| Index HbA1c | |||||
|---|---|---|---|---|---|
| <6.1% (<43 mmol/mol) | 6.1–6.5% (43–48 mmol/mol) | 6.6–7.4% (49–57 mmol/mol) | 7.5–8.0% (58–64 mmol/mol) | >8.0% (>64 mmol/mol) | |
| N | 1461 | 1597 | 2871 | 1168 | 4108 |
| Age, median (IQR) | 64 (56;73) | 66 (58;75) | 65 (57;74) | 65 (56;74) | 62 (54;71) |
| Sex, percent Male | 50.4 | 48.3 | 50.6 | 51.6 | 55.5 |
| HbA1c | |||||
| Index, median (IQR) | 5.7 (5.4;5.9) | 6.3 (6.2;6.5) | 6.9 (6.7;7.2) | 7.7 (7.6;7.9) | 9.6 (8.7;11.0) |
| Measurements*, median (IQR) | 4 (3;6) | 5 (3;6) | 5 (3;7) | 6 (4;7) | 6 (4;8) |
| Mean residual, median (IQR) | 0.25 (0.17;0.38) | 0.29 (0.19;0.46) | 0.43 (0.28;0.67) | 0.61 (0.41;0.90) | 1.18 (0.70;2.07) |
| Absolute change, median (IQR) | 0.30 (−0.10;0.70) | 0.10 (−0.30;0.60) | −0.10 (−0.60;0.60) | −0.40 (−1.10;0.50) | −1.90 (−3.60;−0.50) |
| Preventive pharmacological treatment of cardiovascular diseases, percent | 66.4 | 68.2 | 67.7 | 66.7 | 61.4 |
| Prior cardiovascular disease, percent | 21.4 | 21.7 | 22.9 | 23.4 | 20.0 |
| Number of non-cardiovascular disease, median (IQR) | 5 (3;6) | 5 (3;7) | 6 (4;7) | 6 (4;8) | 7 (5;8) |
| Deaths, n (percent) | 342 (23.4) | 378 (23.7) | 713 (24.8) | 354 (30.3) | 1043 (25.4) |
| Follow-up time | |||||
| Total, years | 8081 | 8724 | 16 340 | 7018 | 24 666 |
| Per individual, days median (IQR) | 1993 (1329;2936) | 1978 (1323;2768) | 2097 (1412;3001) | 2408 (1482; 3079) | 2376 (1531;3049) |
*Number of measurements between index HbA1c and closing HbA1c.
HbA1c, glycated hemoglobin.