Anthropometric data on the 40 male study participants according to CD300LG rs72836561 CC and CT genotype
| Variable | CC (n=20) | CT (n=20) | p-Value |
|---|---|---|---|
| Anthropometry | |||
| Age (years) | 55.1 (50.8 to 59.2) | 55.0 (50.8 to 59.3) | 0.99 |
| BMI (kg/m2) | 24.6 (23.8 to 25.5) | 24.5 (23.4 to 25.6) | 0.79 |
| Systolic blood pressure (mm Hg) | 130 (126 to 133) | 140 (132 to 147) | 0.02 |
| Diastolic blood pressure (mm Hg) | 78 (75 to 82) | 84 (81 to 87) | 0.02 |
| Waist circumference (cm) | 91.9 (88.5 to 95.4) | 92.5 (89.0 to 95.9) | 0.82 |
| Current smokers (yes/no) | 1/19 | 5/15 | 0.18 |
| Body composition from DXA scan | |||
| Lean body mass (kg) | 59.0 (56.7 to 61.3) | 58.3 (55.3 to 61.4) | 0.72 |
| Fat mass (kg) | 16.9 (15.1 to 18.6) | 16.9 (15.0 to 18.8) | 0.99 |
| Fat per cent (%) | 21.4 (19.6 to 23.2) | 21.5 (19.9 to 23.1) | 0.90 |
| Fasting blood samples | |||
| HbA1c (IFCC, mmol/mol) | 35.2 (33.8 to 36.5) | 35.7 (34.5 to 36.9) | 0.56 |
| HbA1c (%) | 5.4 (5.2 to 5.5) | 5.4 (5.3 to 5.5) | 0.65 |
| Glucose (mmol/L) | 5.4 (5.3 to 5.6) | 5.5 (5.2 to 5.7) | 0.81 |
| Total cholesterol (mmol/L) | 5.3 (5.0 to 5.6) | 5.1 (4.7 to 5.4) | 0.18 |
| LDL (mmol/L) | 3.4 (3.1 to 3.7) | 3.1 (2.8 to 3.4) | 0.19 |
| HDL (mmol/L)* | 1.4 (1.1 to 1.7) | 1.2 (1.0 to 1.5) | 0.42 |
| Triglyceride (mmol/L)* | 1.1 (0.8 to 1.4) | 1.3 (0.7 to 1.7) | 0.49 |
| Insulin (pmol/L)* | 34.7 (24.5 to 50.0) | 39.7 (26.8 to 54.0) | 0.61 |
| Proinsulin (pmol/L)* | 3.41 (2.71 to 4.80) | 4.00 (2.73 to 5.44) | 0.26 |
| Proinsulin/insulin ratio | 0.12 (0.09 to 0.15) | 0.13 (0.10 to 0.15) | 0.67 |
| C-peptide (pmol/L)* | 362 (283 to 384) | 375 (292 to 544) | 0.22 |
| Proinsulin/C-peptide | 0.011 (0.009 to 0.013) | 0.012 (0.009 to 0.014) | 0.78 |
| HOMA-B (%) | 55.3 (44.7 to 65.9) | 61.8 (47.4 to 76.1) | 0.45 |
| HOMA-IR | 1.27 (1.03 to 1.52) | 1.55 (1.07 to 1.99) | 0.28 |
Mean and 95% CI.
*Median and IQR.
BMI, body mass index; CC, control; CT, polymorphism carriers; HbA1c, glycated haemoglobin; HDL, high-density lipoprotein; IFCC, international federation of clinical chemistry; LDL, low-density lipoprotein.