Renal function at the initial and final stages and its change during the 11-year observation period
| Characteristic | CI (n=12) | CII (n=14) | CIII (n=11) | ANOVA |
|---|---|---|---|---|
| Initial eGFR (mL/min/1.73 m2) | 88.0±14.9 | 93.9±26.1 | 93.9±17.2 | NS |
| Final eGFR (mL/min/1.73 m2) | 76.5±24.4 | 59.9±21.5 | 76.6±13.1 | NS (0.07) |
| Slope of eGFR decline (mL/min/1.73 m2/year) | −1.08±1.23 | −4.11±3.99 | −1.69±1.96 | 0.02 |
| p Value (initial vs final eGFR) | NS | 0.0001 | 0.0058 | – |
| Initial ACR | 25.9 (2.2–277.1) | 50.9 (7.4–169.8) | 15.8 (5.6–251.0) | NS |
| Final ACR | 16.2 (0.2–1403.2) | 162.8 (2.4–4135.9) | 44.9 (3.1–367.2) | NS |
| p Value (initial vs final ACR) | NS | <0.05 | NS | – |
| Initial albuminuria stage (normoalbuminuria/ microalbuminuria/macroalbuminuria) | 7/5/0 | 5/9/0 | 7/4/0 | NS |
| Final albuminuria stage (normoalbuminuria/ microalbuminuria/macroalbuminuria) | 7/3/2 | 4/4/6 | 5/5/1 | NS |
| p Value (initial vs final albuminuria stage) | NS | p<0.05 (χ2=8.0) | NS | – |
ACR, albumin/creatinine ratio; ANOVA, analysis of variance; CI, category I; CII, category II; CIII, category III; eGFR, estimated glomerular filtration rate; NS, not significant.