Age-adjusted prevalence of CKD in T2DM
| Overall | NHANES 2007–2008 | NHANES 2009–2010 | NHANES 2011–2012 | |||||
|---|---|---|---|---|---|---|---|---|
| eGFR determined by CKD-EPI | N | % (95% CI) | N | % (95% CI) | N | % (95% CI) | N | % (95% CI) |
| No CKD | 1122 | 61.7 (59.2 to 64.2) | 380 | 59.8 (56.2 to 63.5) | 391 | 63.1 (58.6 to 67.6) | 351 | 62.4 (57.3 to 67.5) |
| CKD all stages | 884 | 38.3 (35.8 to 40.8) | 316 | 40.2 (36.5 to 43.8) | 293 | 36.9 (32.4 to 41.4) | 275 | 37.6 (32.5 to 42.7) |
| Stage 1 (eGFR ≥90 and UACR ≥30 mg/g) | 201 | 9.1 (7.5 to 10.7) | 84 | 11.4 (8.2 to 14.7) | 60 | 6.9 (5.1 to 8.8) | 57 | 8.7 (5.7 to 11.7) |
| Stage 2 (eGFR 60–89 and UACR ≥30 mg/g) | 221 | 9.4 (7.7 to 11.2) | 88 | 11.2 (8.3 to 14.0) | 71 | 9.8 (6.0 to 13.5) | 62 | 7.5 (4.8 to 10.2) |
| Stage 3a (eGFR 45–59) | 257 | 11.2 (9.7 to 12.8) | 78 | 9.4 (7.3 to 11.6) | 87 | 10.8 (8.0 to 13.6) | 92 | 13.2 (9.9 to 16.5) |
| Stage 3b (eGFR 30–44) | 133 | 5.5 (4.4 to 6.6) | 41 | 5.4 (2.6 to 8.2) | 52 | 6.4 (4.6 to 8.3) | 40 | 4.9 (3.4 to 6.3) |
| Stage 4 (eGFR 15–29) | 48 | 2.4 (1.5 to 3.2) | 18 | 2.3 (1.4 to 3.2) | 14 | 2.0 (1.0 to 3.0) | 16 | 2.7 (0.5 to 4.9) |
| Stage 5 (eGFR <15) | 24 | 0.7 (0.0 to 1.0) | 7 | 0.5 (0.0 to 0.9) | 9 | 1.0 (0.0 to 1.9) | 8 | 0.6 (0.1 to 1.1) |
| Total | 2006 | 100 | 696 | 100 | 684 | 100 | 626 | 100 |
Age adjustment is based on the age distribution of diagnosed diabetes in US adults (18+years), which is derived from the following US Census Bureau data: 2012 Current Population Survey—Annual Social and Economic Supplement, and 2012 National Health Interview Survey—Diagnosed Diabetes. The estimated age distribution of diagnosed diabetes is 12.58% for age 18–44, 48.33% for age 45–64, and 39.09% for age 65+.
CKD, chronic kidney disease; CKD-EPI, the Chronic Kidney Disease Epidemiology Collaboration equation; eGFR, estimated glomerular filtration rate (mL/min/1.72 m2); UACR, urinary albumin:creatinine ratio (mg/g).