NMR-derived lipoprotein particle concentrations and sizes in overweight/obese African-American and white American women with pre-diabetes
| Parameter | Groups | African-Americans | White Americans | p Value |
|---|---|---|---|---|
| N | 110 | 69 | 41 | |
| VLDL size (nm) | 46.4±6.7 | 44.9±6.04 | 48.6±6.9 | 0.004 |
| LDL size (nm) | 20.1±0.51 | 21.1±0.47 | 20.7±0.54 | 0.01 |
| HDL size (nm) | 9.0±0.51 | 9.2±0.5 | 8.9±0.5 | 0.009 |
| VLDL and chylomicron particles (total) (nmol/L) | 46.4±26.8 | 38.9±24.8 | 59.2±25.6 | <0.001 |
| Large VLDL and chylomicron particles (nmol/L) | 3.3±3.9 | 2.4±3.4 | 4.9±4.1 | 0.0007 |
| Medium VLDL particles (nmol/L) | 18.3±15 | 13.7±12.2 | 25.9±16.2 | 0.0001 |
| Small VLDL particles (nmol/L) | 24.9±14.1 | 22.9±13.9 | 28.3±13.8 | 0.05 |
| Total LDL particles (nmol/L) | 1234.3±349.5 | 1226.2±378.3 | 1248.2±286.5 | 0.732 |
| IDL particles (nmol/L) | 120.2±81.8 | 126.9±87.6 | 109±70.5 | 0.267 |
| Large LDL particles (nmol/L) | 538.2±190.1 | 560.5.4±197 | 500.8±176.1 | 0.113 |
| Small LDL particles (nmol/L) | 575.9±286.8 | 538.8±294.1 | 638.4±266 | 0.07 |
| Total HDL particles (µmol/L) | 33.6±5.7 | 33.9±5.c8 | 33.1±5.4 | 0.47 |
| Large HDL particles (µmol/L) | 5.6±3.2 | 6.1±3.1 | 4.64±3.1 | 0.02 |
| Medium HDL particles (µmol/L) | 10.7±5.4 | 10.7±5.4 | 10.5±5.4 | 0.86 |
| Small HDL particles (µmol/L) | 17.9±17. | 17.7±4.9 | 17.9±5.3 | 0.407 |
Values are mean±SD.
HDL, high-density lipoprotein; IDL, intermediate-density lipoprotein; LDL, low-density lipoprotein; NMR, nuclear magnetic resonance; VLDL, very low-density lipoprotein.