Sensitivity, specificity, PPV and NPV of the GDRS according to selected cut-offs of predicted 5-year diabetes risk in the ‘GNHIES98—longitudinal sample’ (N=3625) and the ‘DEGS1—cross-sectional sample’ (N=6048)
| Predicted 5-year diabetes risk (%) | GDRS points* (≈) | GNHIES98—longitudinal sample | DEGS1—cross-sectional sample | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Prediction of incident diagnosed type 2 diabetes | Detection of prevalent undiagnosed diabetes | ||||||||
| Sensitivity | Specificity | PPV | NPV | Sensitivity | Specificity | PPV | NPV | ||
| 1.0 | 480 | 0.97 | 0.49 | 0.04 | 1.00 | 0.95 | 0.50 | 0.04 | 1.00 |
| 2.0 | 550 | 0.96 | 0.64 | 0.06 | 1.00 | 0.91 | 0.63 | 0.05 | 1.00 |
| 2.5 | 572 | 0.96 | 0.69 | 0.06 | 1.00 | 0.89 | 0.67 | 0.05 | 1.00 |
| 3.0 | 590 | 0.95 | 0.72 | 0.07 | 1.00 | 0.88 | 0.70 | 0.06 | 1.00 |
| 4.0 | 619 | 0.84 | 0.78 | 0.08 | 1.00 | 0.81 | 0.75 | 0.07 | 0.99 |
| 5.0 | 641 | 0.75 | 0.81 | 0.08 | 0.99 | 0.78 | 0.79 | 0.07 | 0.99 |
| 10.0 | 711 | 0.51 | 0.91 | 0.12 | 0.99 | 0.61 | 0.89 | 0.11 | 0.99 |
| 15.0 | 751 | 0.27 | 0.95 | 0.10 | 0.98 | 0.44 | 0.93 | 0.13 | 0.99 |
| 20.0 | 780 | 0.20 | 0.97 | 0.12 | 0.98 | 0.36 | 0.96 | 0.14 | 0.99 |
*In the ‘GNHIES98—longitudinal sample’, GDRS points ranged from 115.4 to 1000.5 points. In the ‘DEGS1—cross-sectional sample’, GDRS points ranged from 77.3 to 1128.2 points.
DEGS1, German Health Interview and Examination Survey for Adults; GDRS, German Diabetes Risk Score; GNHIES98, German National Health Interview and Examination Survey 1998; NPV, negative predictive value; PPV, positive predictive value.