The correlation of SerpinB1 with multiple variables in patients with type 2 diabetes
| R | p Value | |
|---|---|---|
| Age (years) | 0.3042 | 0.1022 |
| BMI (kg/m2) | −0.2369 | 0.2075 |
| FPG (mg/dL) | 0.1106 | 0.5678 |
| HbA1c (%) | 0.1262 | 0.5064 |
| SBP (mm Hg) | 0.2480 | 0.1864 |
| DBP (mm Hg) | 0.0091 | 0.9619 |
| TG (mg/dL) | −0.1168 | 0.5387 |
| HDL-C (mg/dL) | 0.2434 | 0.1949 |
| LDL-C (mg/dL) | −0.4515 | 0.0123* |
| Insulin (μU/mL) | −0.0607 | 0.7544 |
| UA (mg/dL) | −0.0692 | 0.7164 |
| log10 hsCRP (mg/L) | 0.0282 | 0.8845 |
| log10 AST (U/L) | −0.0277 | 0.8846 |
| log10 ALT (U/L) | −0.1512 | 0.4520 |
| log10 GGT (U/L) | −0.1239 | 0.5141 |
| eGFR (mL/min/1.73 m2) | −0.3013 | 0.1056 |
| CAVI index | −0.1182 | 0.5823 |
All variables except for hsCRP, AST, ALT, and GGT followed a normal distribution as confirmed by a χ2 goodness of fit test. Because of the skewed distribution for hsCRP, AST, ALT, and GGT, these variables are log10-transformed. After log10-transforming, these variables followed a normal distribution.
All correlations were evaluated using Pearson's correlation coefficient, R.
The number of patients for various markers were 30 except for FPG (n=29), Insulin (n=29), hsCRP (n=29), CAVI index (n=24).
*p<0.05 is defined as statistical significance.
ALT, alanine transaminase; GGT, gamma-glutamyl transpeptidase; AST, aspartate transaminase; BMI, body mass index; CAVI, cardio-ankle vascular index; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; FPG, fasting plasma glucose; HbA1c, hemoglobin A1c; HDL-C, high-density lipoprotein cholesterol; hsCRP, high-sensitivity C reactive protein; LDL-C, low-density lipoprotein cholesterol; SBP, systolic blood pressure; TG, triglyceride; UA, uric acid.