HbA1c values and the suspected diagnosis of (pre)diabetes* in patients with and without diabetes based on medical history
| Control (n=109) | Mild/moderate periodontitis (n=126) | Severe periodontitis (n=78) | p Value | |
|---|---|---|---|---|
| Diabetes, Hx (%)† | 3 (2.8%) | 5 (4.0%) | 6 (7.7%) | 0.256 |
| HbA1c (%) (mmol/mol) | ||||
| All subjects‡ | 5.7±0.7 (39±8) | 6.1±1.4 (43±15) | 6.3±1.3§ (45±15) | 0.003 |
| Subjects without diabetes¶** | 5.7±0.6 (38±7) | 6.0±1.3 (42±15) | 6.2±1.2§ (44±13) | 0.009 |
| Number of suspected diagnosis (%) | ||||
| All subjects‡ | 0.010 | |||
| Healthy | 58 (53.2%) | 51 (40.5%) | 23 (29.5%) | |
| Pre-diabetes | 40 (36.7%) | 58 (46.0%) | 37 (47.4%) | |
| Diabetes | 11 (10.1%) | 17 (13.5%) | 18 (23.1%) | |
| Subjects without diabetes¶** | 0.024 | |||
| Healthy | 58 (54.7%) | 51 (42.1%) | 23 (31.9%) | |
| Pre-diabetes | 39 (36.8%) | 58 (47.9%) | 36 (50.0%) | |
| Diabetes | 9 (8.5%) | 12 (9.9%) | 13 (18.1%) | |
Data are presented as the mean±SD or as n (%).
*(Pre)diabetes classification according to the ADA guidelines 2015.
†Based on the medical history (Hx).
‡Subjects with and without diabetes based on the medical history are included.
§Bonferroni test: p value <0.05 compared with control.
¶Subjects with diabetes based on the medical history are excluded.
**Control: n=106; mild/moderate periodontitis: n=121; severe periodontitis: n=72.
ADA, American Diabetes Association; HbA1c, glycated hemoglobin.http://dx.doi.org/10.1136/bmjdrc-2016-000326