Postprandial values of the subjects studied
| Variables | Healthy (n=10) | IGT+reduced FPIS (n=8) | IGT+preserved FPIS (n=14) | p |
| Glucose 5’ | 174.1±30.4 | 205.5±25.3 | 191.6±30.1 | 0.073 |
| Glucose 10’ | 160.8±24.5 | 185.7±23.7 | 175.6±23.07 | 0.043 |
| AUC glucose 0–30’ | 3968 (3494–4697) | 5358 (5161–5801) | 4667 (4310–5416) | <0.001 |
| AUC glucose 0–120’ | 11200 (9338–12 911) | 16748 (16 053–18 359) | 12872 (11 234–15 283) | <0.001 |
| Insulin 5’ | 37.8 (26.5–57.0) | 15.9 (8.4–23.1) | 47.1 (16.4–60.7) | 0.006 |
| Insulin 10’ | 34.9 (20.1–43.1) | 19.5 (12.8–26.3) | 49.5 (29.5–59.4) | 0.004 |
| AUC insulin 0–10’ | 300 (194–419) | 151 (101–202) | 417 (193–518) | <0.001 |
| AUC insulin 0–30’ | 928 (527–1097) | 665 (464–778) | 1160 (844–1456) | <0.001 |
| AUC insulin 0–120’ | 2020 (1039–2692) | 2784 (2623–3182) | 3423.3 (1958.3–4213.4) | 0.04 |
The results are expressed as mean±SD for normally distributed variables, and medians (IQR) for variables with non-parametric distribution. To make the comparison between the 3 groups, Kruskal-Wallis test was used.
Glucose in mg/dL; insulin in µIU/mL; glucose AUC in mg/dL/min; insulin AUC in µIU/mL/min. Measurement of glucose and insulin after intravenous glucose load.
AUC, area under the curve; FPIS, first-phase insulin secretion; IGT, impaired glucose tolerance.