Table 3

Bivariate ORs comparing patient characteristics at different HbA1c ranges

Variable	Comparison	Moderate vs tight control: HbA1c 7%–8.5% vs. HbA1c <7%		Not controlled vs tight control: HbA1c>8.5% vs. HbA1c <7%		Not controlled vs moderate control: HbA1c >8.5% vs HbA1c 7%–8.5%
Variable	Comparison	OR (95% CI)	p Value	OR (95% CI)	p Value	OR (95% CI)	p Value
Age range in years	40–49 vs 80+	1.11 (0.92 to 1.35)	0.3	3.35 (2.66 to 4.21)	<0.0001	3.03 (2.93 to 3.83)	<0.0001
	50–59 vs 80+	1.20 (1.04 to 1.38)	0.01	2.93 (2.43 to 3.54)	<0.0001	2.45 (2.02 to 2.97)	<0.0001
	60–69 vs 80+	1.14 (1.01 to 1.30)	0.04	1.84 (1.54 to 2.21)	<0.0001	1.62 (1.35 to 1.95)	<0.0001
	70–79 vs 80+	1.18 (1.04 to 1.35)	0.01	1.28 (1.05 to 1.55)	0.02	1.08 (0.88 to 1.32)	0.5
Number of comorbidities*	0–1 vs 3+	1.48 (1.27 to 1.74)	<0.0001	1.64 (1.33 to 2.01)	<0.0001	1.10 (0.89 to 1.36)	0.4
Number of comorbidities*	2–3 vs 3+	1.24 (1.08 to 1.43)	0.002	1.3 (1.09 to 1.56)	0.004	1.05 (0.87 to 1.27)	0.6
Gender	Male vs female	1.10 (1.05 to 1.16)	0.0002	1.21 (1.13 to 1.29)	<0.0001	1.10 (1.02 to 1.18)	0.01
sBP >130 mm Hg	Yes vs no	1.14 (1.08 to 1.21)	<0.0001	1.16 (1.08 to 1.24)	<0.0001	1.02 (0.94 to 1.1)	0.7
LDL >2 mmol/L	Yes vs no	0.73 (0.69 to 0.77)	<0.0001	1.02 (0.95 to 1.1)	0.5	1.41 (1.3 to 1.52)	<0.0001
Urine ACR>2	Yes vs no	1.26 (1.17 to 1.36)	<0.0001	1.87 (1.7 to 2.05)	<0.0001	1.48 (1.34 to 1.63)	<0.0001
BMI	Overweight vs normal/underweight	1.17 (1.07 to 1.29)	0.0009	1.01 (0.89 to 1.15)	0.9	0.86 (0.75 to 1)	0.04
BMI	Obese vs normal/underweight	1.34 (1.22 to 1.46)	<0.0001	1.5 (1.33 to 1.69)	<0.0001	1.13 (0.99 to 1.29)	0.07
Number of primary care encounters	6–16 vs 0–5	1.01 (0.93 to 1.09)	0.8	0.80 (0.72 to 0.88)	<0.0001	0.79 (0.71 to 0.89)	<0.0001
Number of primary care encounters	17+ vs −0–5	1.13 (1.04 to 1.23)	0.01	1.01 (0.91 to 1.12)	0.9	0.89 (0.8 to 1)	0.06
Number of medication classes prescribed^†	1 vs 0	1.6 (1.50 to 1.71)	<0.0001	1.03 (0.93 to 1.14)	0.5	0.64 (0.58 to 0.71)	<0.0001
	2 vs 0	3.06 (2.76 to 3.39)	<0.0001	2.81 (2.46 to 3.21)	<0.0001	0.92 (0.81 to 1.05)	0.2
	3+ vs 0	5.36 (4.84 to 5.94)	<0.0001	8.85 (7.91 to 9.89)	<0.0001	1.65 (1.5 to 1.82)	<0.0001

*Includes the CPCSSN validated comorbidities only (hypertension, chronic obstructive pulmonary disease, depression, osteoarthritis, dementia, epilepsy, Parkinson's disease).
†A prescription for insulin automatically included a patient in group 3.
ACR, albumin to creatinine ratio; BMI, body mass index; HbA1c, hemoglobin A1c; LDL, low density lipoprotein; sBP, systolic blood pressure.