Acute | Non-acute | p Value | |
Number (%) | 146 (56) | 116 (44) | - |
Age (years) | 57±11 | 57±11 | 0.58 |
Male (%) | 94 (64) | 70 (61) | 0.50 |
BMI (kg/m2) | 34±14 | 34±13 | 0.37 |
Duration of diabetes (years)* | 10 (5–17) | 8 (4–13) | 0.05 |
Retinopathy grade (n (%)) | n=131 | n=113 | |
None | 30 (23) | 61 (54) | |
Minimal-moderate | 35 (27) | 27 (24) | <0.001 |
Severe | 66 (50) | 25 (22) | |
Proteinuria (g/day)* | 5.0 (1.4–10.5) | 2.9 (1.0–5.3) | 0.001 |
Estimated GFR (mL/min/1.73 m2)* | |||
At biopsy | 21 (12–32) | 47 (35–71) | <0.001 |
3 months before biopsy | 43 (30–58) | 48 (34–72) | 0.07 |
Histological diabetic nephropathy (n (%)) | |||
Absent | 25 (17) | 47 (41) | |
Grades 1 and 2 | 15 (10) | 19 (16) | <0.001 |
Grades 3 and 4 | 106 (73) | 50 (43) | |
Non-diabetic renal diseases (n (%)) | |||
Focal segmental glomerulosclerosis | 18 (12.5) | 38 (33) | <0.001 |
Membranous nephropathy | 2 (1.5) | 6 (5) | 0.08 |
Minimal change disease | 0 (0) | 6 (5) | 0.005 |
IgA nephropathy | 0 (0) | 3 (2.5) | 0.05 |
Interstitial nephritis | 32 (22) | 8 (7) | 0.001 |
Immune complex glomerulonephritides | 21 (14.5) | 4 (3.5) | 0.003 |
Acute tubular necrosis | 9 (6) | 0 (0) | 0.007 |
Acute pyelonephritis | 3 (2) | 1 (1) | 0.43 |
Others | 2 (1.5) | 7 (6) | 0.04 |
Histological findings | |||
DN grade* | 3 (2–4) | 2 (0–3) | <0.001 |
Sclerosed glomeruli (%) | 35 (17–54) | 30 (11–51) | 0.24 |
Glomerular capillary patency (%) | 50 (25–73) | 80 (40–95) | <0.001 |
Interstitial scarring (%) | 25 (15–49) | 20 (10–35) | <0.001 |
*Results expressed as median (IQR).
BMI, body mass index; DN, diabetic nephropathy; GFR, glomerular filtration rate.