Table 2

HRs with 95% CIs per 1 mmol/L increase in casual glucose levels from Cox proportional hazards models* with glucose analyzed as a continuous variable with and without linear splines in 159 731 Norwegian men and women, followed up to 12.7 years (imputed data)

Events/no.HR (95% CI) for model with linear splines with three knotsHR (95% CI) for model without linear splines
<7.8 mmol/L (normal)†7.8–11.0 mmol/L (borderline)†>11.0 mmol/L (high)†All groups combined†
Acute myocardial infarction6569/159 7311.03 (1.00 to 1.07)1.01 (0.92 to 1.12)1.06 (0.96 to 1.18)1.03 (1.01 to 1.06)
Stroke6117/159 7311.03 (1.00 to 1.07)1.16 (1.06 to 1.28)0.98 (0.89 to 1.09)1.05 (1.03 to 1.07)
Cardiovascular mortality5678/159 7311.06 (1.02 to 1.10)1.11 (1.01 to 1.22)1.04 (0.95 to 1.13)1.07 (1.04 to 1.09)
All-cause mortality17,096/159 7311.05 (1.03 to 1.08)1.13 (1.07 to 1.19)1.00 (0.94 to 1.06)1.06 (1.05 to 1.08)
  • *Adjusted for age, sex, cholesterol, systolic blood pressure, BMI, time since last meal, smoking, education and marital status.

  • †HR per mmol/L increase in casual glucose levels with 95% CI.

  • BMI, body mass index.