Table 3

Multivariable association of impaired awareness of hypoglycemia with clinical parameters, C-peptide continuous log transformed

Full modelForward stepwise model
OR95% CIP valueOR95% CIP value
Diabetes duration1.02(0.99 to 1.04)0.261
Log age at onset of diabetes, years4.01(1.63 to 9.86)0.0033.99(1.77 to 9.01)0.001
BMI, kg/m21.07(1.02 to 1.13)0.0111.08(1.03 to 1.14)0.003
Hypertension1.20(0.63 to 2.32)0.576
Microvascular complications1.83(1.00 to 3.33)0.0482.28(1.34 to 3.90)0.003
Macrovascular complications1.52(0.56 to 4.18)0.414
Log C-peptide, pmol/L0.66(0.42 to 1.02)0.0620.63(0.40 to 0.98)0.040
eGFR (CKD-EPI), mL/min/1.73 m21.00(0.99 to 1.02)0.954
Beta-blocker use0.74(0.26 to 2.17)0.589
  • BMI, body mass index; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; eGFR, estimated glomerular filtration rate.