The Dallas Heart Study: a population-based probability sample for the multidisciplinary study of ethnic differences in cardiovascular health☆
Section snippets
Human subjects protection
A community advisory board was established and aided in the wording of subject consent forms, which were approved by the institutional review boards at the University of Texas Southwestern and the Research Triangle Institute (which was responsible for developing the sampling frame, selecting the sample, screening the households, and conducting the household interview) in accordance with the Helsinki Declaration of the World Medical Association.
Sampling requirements
We recruited a probability sample with equal
Participation rates
We enrolled a much larger percentage of black patients than any other cardiovascular study that collected a probability sample, and our participation rates compare favorably with those of other health surveys in American adults (TABLE 1, TABLE 2). 14, 15, 16, 17, 18, 19, 20
Validity of population estimates from the weighted interview sample
The Dallas Heart Study estimates for the stratification variables (ethnicity, gender, and age) were identical to those from the 2000 United States census (Table 3). The estimated population distribution of educational
Discussion
The Dallas Heart Study represents a departure from previous cardiovascular health surveys6, 14, 15, 16, 17, 18, 19, 20, 21 by accessing a multiethnic, population-based probability sample to pinpoint key sources of ethnic differences in cardiovascular health at the community level and to probe the mechanistic basis of such differences using state-of-the-art imaging modalities, comprehensive genotyping, and general clinical research center methods. Detailed information regarding social and
Acknowledgements
We wish to acknowledge our gratitude to the Community Advisory Board members and for the support of the Dallas community. Dallas Heart Study investigators in the Donald W. Reynolds Cardiovascular Clinical Research Center include Ronald G. Victor, Helen H. Hobbs, Scott M. Grundy, Eric N. Olson, and R. Sanders Williams (University of Texas Southwestern Medical Center principal investigators); Richard S. Cooper (Loyola University), David S. Siscovick (University of Washington), and Joseph A. Hill
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The Dallas Heart Study is funded by a center grant from the Donald W. Reynolds Foundation, Las Vegas, Nevada. Survey instrument development was funded in part by a Patient Care and Outcomes Research Grant from the American Heart Association, Dallas, Texas, to Dr. Victor.