Background Intraportal transplantation of pancreatic islets offers improved glycaemic control
and insulin independence in type 1 diabetes mellitus, but intraportal thrombosis remains a …

Islet amyloid polypeptide is a novel 37 amino-acid-residues polypeptide which has been
isolated from amyloid deposits in an insulinoma, and in human and cat islets of Langerhans …

There are strong indications that only a small fraction of grafts successfully engraft in clinical
islet transplantation. One explanation may be the instant blood-mediated inflammatory …

Aims/hypothesis Based on mouse study findings, pancreatic islet cells are supposed to lack
basement membrane (BM) and interact directly with vascular endothelial BM. Until now, the …

Selective targeting of endothelial cells in tumor vessels requires delineation of key
molecular events in formation and survival of blood vessels within the tumor …

Cytotoxic T lymphocytes eliminate infected and tumor cells mainly by perforin/granzyme-
induced apoptosis. Earlier studies suggested that serglycin-proteoglycans form …

In samples obtained during the autopsies of 2 patients with sarcoidosis, genetic material
from Rickettsia helvetica was detected by polymerase chain reaction, and histologic and …

SG (serglycin) PGs (proteoglycans) are strongly implicated in the assembly of MC (mast cell)
granules. However, this notion has mainly been on the basis of studies of MCs of the …

The extent of apoptosis identified by in situ DNA nick end labelling (TUNEL) on tissue
samples obtained from patients with neuroendocrine tumors was correlated with the clinical …

Synaptic vesicle protein 2 (SV2) is a glycoprotein identified in the nervous system of several
species, including man, but its occurrence in the human neuroendocrine (NE) cell system …