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Pregnancy outcomes in women with onset of type 1 diabetes mellitus less than 18 years of age
  1. Roy Gavin Stone1,
  2. Paul Scully2,
  3. Emma Troy3,
  4. Yvonne Moloney4,
  5. Anne Quinn1,
  6. Eoin Noctor2,3,
  7. Orla Neylon1,2,
  8. John Slevin4,
  9. Annemarie Murphy1,2,
  10. Clodagh O'Gorman1,2
  1. 1Department of Paediatrics, University Hospital Limerick, Dooradoyle, Limerick, Ireland
  2. 2Graduate Entry Medical School, University of Limerick, Limerick, Ireland
  3. 3Department of General Medicine, University Hospital Limerick, Dooradoyle, Limerick, Ireland
  4. 4Department of Obstetrics, University Maternity Hospital Limerick, Limerick, Ireland
  1. Correspondence to Dr Roy Gavin Stone; roygavinstone{at}


Background Pregnancy in women with type 1 diabetes mellitus (T1DM) is associated with an increased risk of congenital malformations, obstetric complications and neonatal morbidity. This study aims to investigate maternal, perinatal and neonatal outcomes of pregnancies in women with onset of T1DM less than 18 years of age.

Methods This retrospective cohort study extracted data regarding prenatal, intrapartum and postnatal outcomes of pregnancies in women with onset of T1DM<18 years identified from the diabetes in pregnancy register at University Maternity Hospital Limerick, treated from July 1, 2007 to July 1, 2017.

Results Seventeen women with onset of T1DM <18 years gave birth to 23 live infants during the period studied. 73.9% of pregnancies were unplanned. Only 21.7% of pregnancies took preconceptual folic acid. 60.9% of infants required treatment for hypoglycemia.

Conclusion The high prevalence of unplanned pregnancy and poor uptake of prepregnancy care must be improved on in order to improve outcomes for this high-risk group.

  • pregnancy preparedness
  • neonatal
  • type 1

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  • Contributors RGS, PS, ET, YM, AQ, EN, ON, JS, AM and COG contributed to the conception or design of the work. RGS, PS, ET, YM and AQ contributed to the acquisition, analysis and interpretation of data for the work. RGS and ET drafted the manuscript. EN, ON, JS, AM and COG critically revised the manuscript. All authors gave final approval and agreed to be accountable for all aspects of work ensuring integrity and accuracy.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Ethics approval Study approval was granted by University Hospital Limerick’s Ethics Committee.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data availability statement All data relevant to the study are included in the article. All data regarding participants have been deidentified and will be stored according to general data protection regulations.

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