@article {Wadee002246, author = {Alisha N Wade and Ian R Hambleton and Anselm J M Hennis and Christina Howitt and Selvi M Jeyaseelan and Nkemcho O Ojeh and Angela M C Rose and Nigel Unwin}, title = {Anthropometric cut-offs to identify hyperglycemia in an Afro-Caribbean population: a cross-sectional population-based study from Barbados}, volume = {9}, number = {1}, elocation-id = {e002246}, year = {2021}, doi = {10.1136/bmjdrc-2021-002246}, publisher = {BMJ Specialist Journals}, abstract = {Introduction Body mass index (BMI) and waist circumference (WC) cut-offs associated with hyperglycemia may differ by ethnicity. We investigated the optimal BMI and WC cut-offs for identifying hyperglycemia in the predominantly Afro-Caribbean population of Barbados.Research design and methods A cross-sectional study of 865 individuals aged >=25 years without known diabetes or cardiovascular disease was conducted. Hyperglycemia was defined as fasting plasma glucose >=5.6 mmol/L or hemoglobin A1c >=5.7\% (39 mmol/mol). The Youden index was used to identify the optimal cut-offs from the receiver operating characteristic (ROC) curves. Further ROC analysis and multivariable log binomial regression were used to compare standard and data-derived cut-offs.Results The prevalence of hyperglycemia was 58.9\% (95\% CI 54.7\% to 63.0\%). In women, optimal BMI and WC cut-offs (27 kg/m2 and 87 cm, respectively) performed similarly to standard cut-offs. In men, sensitivities of the optimal cut-offs of BMI >=24 kg/m2 (72.0\%) and WC >=86 cm (74.0\%) were higher than those for standard BMI and WC obesity cut-offs (30.0\% and 25\%{\textendash}46\%, respectively), although with lower specificity. Hyperglycemia was 70\% higher in men above the data-derived WC cut-off (prevalence ratio 95\% CI 1.2 to 2.3).Conclusions While BMI and WC cut-offs in Afro-Caribbean women approximate international standards, our findings, consistent with other studies, suggest lowering cut-offs in men may be warranted to improve detection of hyperglycemia. Our findings do, however, require replication in a new data set.No data are available.}, URL = {https://drc.bmj.com/content/9/1/e002246}, eprint = {https://drc.bmj.com/content/9/1/e002246.full.pdf}, journal = {BMJ Open Diabetes Research and Care} }