TY - JOUR T1 - The 12-Item Hypoglycemia Impact Profile (HIP12): psychometric validation of a brief measure of the impact of hypoglycemia on quality of life among adults with type 1 or type 2 diabetes JF - BMJ Open Diabetes Research & Care JO - BMJ Open Diab Res Care DO - 10.1136/bmjdrc-2022-002890 VL - 10 IS - 4 SP - e002890 AU - Melanie Broadley AU - Hannah Chatwin AU - Uffe Søholm AU - Stephanie A Amiel AU - Jill Carlton AU - Bastiaan E De Galan AU - Christel Hendrieckx AU - Rory J McCrimmon AU - Søren E Skovlund AU - Frans Pouwer AU - Jane Speight A2 - , Y1 - 2022/08/01 UR - http://drc.bmj.com/content/10/4/e002890.abstract N2 - Introduction The aim of this study was to determine the psychometric properties of the 12-Item Hypoglycemia Impact Profile (HIP12), a brief measure of the impact of hypoglycemia on quality of life (QoL) among adults with type 1 (T1D) or type 2 diabetes (T2D).Research design and methods Adults with T1D (n=1071) or T2D (n=194) participating in the multicountry, online study, ‘Your SAY: Hypoglycemia’, completed the HIP12. Psychometric analyses were undertaken to determine acceptability, structural validity, internal consistency, convergent/divergent validity, and known-groups validity.Results Most (98%) participants completed all items on the HIP12. The expected one-factor solution was supported for T1D, T2D, native English speaker, and non-native English speaker groups. Internal consistency was high across all groups (ω=0.91–0.93). Convergent and divergent validity were satisfactory. Known-groups validity was demonstrated for both diabetes types, by frequency of severe hypoglycemia (0 vs ≥1 episode in the past 12 months) and self-treated episodes (<2 vs 2–4 vs ≥5 per week). The measure also discriminated by awareness of hypoglycemia in those with T1D.Conclusions The HIP12 is an acceptable, internally consistent, and valid tool for assessing the impact of hypoglycemia on QoL among adults with T1D. The findings in the relatively small sample with T2D are encouraging and warrant replication in a larger sample.Data are available upon reasonable request. Data are available on reasonable request via contact with the corresponding author (http://orcid.org/0000-0003-4408-6304), provided that data are to be used for research projects related to health sciences. Data are deidentified participant responses from a web-based quantitative survey. ER -