Patterns of treatment revision for members on common oral antidiabetic medication regimens
| Patterns of treatment revision | n | Per cent |
|---|---|---|
| Baseline treatment=metformin/sulfonylurea (n=418) | ||
| Switch to basal insulin | 99 | 23.7 |
| Add thiazolidinedione | 92 | 22.0 |
| Switch thiazolidinedione | 56 | 13.4 |
| Add basal insulin | 53 | 12.7 |
| Switch non-basal insulin | 29 | 6.9 |
| Add non-basal insulin | 20 | 4.8 |
| All others | 69 | 16.5 |
| Baseline treatment=sulfonylurea (n=366) | ||
| Add metformin | 112 | 30.6 |
| Switch metformin | 90 | 24.6 |
| Switch basal insulin | 50 | 13.7 |
| Add thiazolidinedione | 38 | 10.4 |
| Switch thiazolidinedione | 27 | 7.4 |
| Add basal insulin | 17 | 4.6 |
| All others | 32 | 8.7 |
| Baseline treatment=metformin (n=342) | ||
| Addition | ||
| Switch sulfonylurea | 136 | 39.8 |
| Add sulfonylurea | 95 | 27.8 |
| Add thiazolidinedione | 27 | 7.9 |
| Add basal insulin | 26 | 7.6 |
| Switch basal insulin | 20 | 5.9 |
| Switch thiazolidinedione | 11 | 3.2 |
| All others | 27 | 7.8 |
| Baseline treatment=3+ orals (n=197) | ||
| Switch basal insulin | 38 | 19.3 |
| Add basal insulin | 35 | 17.8 |
| Switch metformin | 20 | 10.2 |
| Switch thiazolidinedione | 20 | 10.2 |
| Add metformin | 14 | 7.1 |
| Add non-basal insulin | 9 | 4.5 |
| All others | 61 | 30.9 |
Per cent reported is based on the sample size within each of the baseline treatment categories.