Mean preprandial BGL, mean postprandial glycemic excursion at 60, 120, and 180 min, peak postprandial glycemic excursion, time to peak postprandial glycemic excursion and mean 120 min AUC following an SB and an EB of equal total insulin dose delivered over 120 min
| SB | EB2HR | |
|---|---|---|
| Preprandial BGL (mmol/L) | 8.5±3.3 | 8.8±3.0 |
| Mean 60 min postprandial glycemic excursion (mmol/L) | 2.9±2.7 | 4.7±4.2* |
| Mean 120 min postprandial glycemic excursion (mmol/L) | 1.8±1.0 | 3.1±1.0 |
| Mean 180 min postprandial glycemic excursion (mmol/L) | −0.4±4.5 | −3.3±3.6* |
| Peak postprandial glycemic excursion (mmol/L) | 4.1±3.5 | 5.9±3.5 |
| Time to peak postprandial glycemic excursion (mins) | 60±35.1 | 71.1±45.2 |
| Mean 120 min AUC (mmol/h/L) | 249.1±68.7 | 440.3±91.6* |
*p<0.05.
AUC, area under the curve; BGL, blood glucose levels; EB, extended bolus; SB, standard bolus.