B | Exp. B | 95% CI | p Value | |
---|---|---|---|---|
Block 1. Demographic variables | ||||
Age | 0.15 | 1.02 | 0.99 to 1.04 | 0.226 |
Gender (male) | 0.70 | 1.07 | 0.60 to 2.03 | 0.830 |
White ethnicity (AA) | 1.365 | 3.92 | 0.92 to 16.66 | 0.065 |
Other ethnicity (AA) | 1.332 | 3.79 | 0.34 to 42.04 | 0.278 |
Block 2. Clinical variables | ||||
Age | 0.019 | 1.02 | 0.99 to 1.04 | 0.137 |
Gender (male) | −0.501 | 0.61 | 0.30 to 1.22 | 0.162 |
White ethnicity (AA) | 1.645 | 5.18 | 1.19 to 22.49 | 0.028 |
Other ethnicity (AA) | 1.403 | 0.07 | 0.34 to 48.32 | 0.266 |
NYHA class III/IV (class I/II) | 0.991 | 2.69 | 1.27 to 5.70 | 0.01 |
Current smoker (non-smoker) | 0.108 | 1.11 | 0.57 to 2.13 | 0.755 |
CAD (no CAD) | −0.872 | 0.42 | 0.21 to 0.82 | 0.011 |
Hypertension (no hypertension) | −0.176 | 0.84 | 0.46 to 1.54 | 0.569 |
BMI | −0.051 | 0.95 | 0.90 to 1.00 | 0.05 |
LVEF | −0.040 | 0.96 | 0.94 to 0.99 | 0.002 |
Antidepressant use (compared to none) | 2.145 | 8.55 | 3.57 to 21.39 | <0.001 |
Block 3. Patient categories based on diabetes and depressive symptoms | ||||
Age | 0.024 | 1.03 | 1.00 to 1.05 | 0.067 |
Gender (male) | −0.683 | 0.51 | 0.24 to 1.05 | 0.067 |
White ethnicity (AA) | 1.789 | 5.98 | 1.38 to 25.99 | 0.02 |
Other ethnicity (AA) | 1.490 | 4.44 | 0.37 to 53.50 | 0.241 |
NYHA class III/IV (class I/II) | 0.974 | 2.65 | 1.23 to 5.69 | 0.013 |
Current smoker (non-smoker) | −0.025 | 0.98 | 0.48 to 1.98 | 0.946 |
CAD (no CAD) | −1.191 | 0.30 | 1.47 to 0.63 | 0.001 |
Hypertension (no hypertension) | −0.286 | 0.36 | 0.41 to 1.38 | 0.358 |
BMI | −0.062 | 0.94 | 0.89 to 0.99 | 0.02 |
LVEF | −0.039 | 0.96 | 0.94 to 0.99 | 0.002 |
Antidepressant use (compared to none) | 2.054 | 7.8 | 3.02 to 20.16 | <0.001 |
Depressive symptoms only (No depressive symptoms and no diabetes) | 0.827 | 2.29 | 1.00 to 5.21 | 0.05 |
Diabetes only (No depressive symptoms and no diabetes) | 0.810 | 2.25 | 0.94 to 5.40 | 0.070 |
Both depressive symptoms and diabetes (No depressive symptoms and no diabetes) | 1.312 | 3.71 | 1.49 to 9.25 | 0.005 |
Cox regression—Overall Model χ2=82.10, df=14, p<0.001.
Comparison group in parentheses.
AA, African-American; BMI, body mass index; CAD, coronary artery disease; LVEF, left ventricular ejection fraction; NYHA, New York Heart Association.