Change in total medication count | Change in diabetes medication | Change in CVD medication | Change in other medication | |||||
---|---|---|---|---|---|---|---|---|
β* | 95% CI | IRR* | 95% CI | β* | 95% CI | β* | 95% CI | |
Number of medications at diagnosis† | −0.49 | −0.56 to −0.42 | – | – | −0.50 | −0.56 to −0.44 | −0.30 | −0.37 to −0.22 |
Male gender | −0.25 | −0.57 to 0.06 | 0.86 | 0.75 to 0.99 | −0.11 | −0.33 to 0.10 | 0.12 | −0.10 to 0.34 |
Intensive treatment arm | 0.44 | 0.10 to 0.78 | 1.14 | 1.01 to 1.30 | 0.39 | 0.09 to 0.69 | −0.08 | −0.30 to 0.13 |
Age at diagnosis (years) | −0.03 | −0.05 to −0.01 | 0.96 | 0.95 to 0.97 | −0.02 | −0.03 to 0.002 | 0.02 | 0.01 to 0.04 |
Modelling 10-year UKPDS CVD risk (%) | 0.04 | 0.02 to 0.05 | 1.02 | 1.01 to 1.03 | 0.02 | 0.01 to 0.03 | 0.00 | −0.01 to 0.01 |
*IRR, Incidence Rate Ratio from a Poisson regression model; β, Regression coefficient from a linear regression model.
†Number of medications of the medication type that is the dependent variable in that columns regression.
CVD, cardiovascular disease; UKPDS, UK Prospective Diabetes Study.