Results of multiple logistic regression analyses
| Predictors of response | OR (95% CI) (unadjusted) | p Value | OR (95% CI) (adjusted) | LRT p Value |
|---|---|---|---|---|
| Baseline HbA1c (%) | 1.53 (1.40 to 1.67) | <0.001 | 1.55 (1.42 to 1.69) | <0.001 |
| BMI categories (kg/m2) | ||||
| Normal | 1 | 1 | ||
| Overweight | 1.35 (0.94 to 1.94) | 0.1 | 1.40 (0.98 to 2.00) | 0.06 |
| Obese | 1.35 (0.95 to 1.91) | 0.09 | 1.50 (1.08 to 2.09) | 0.02 |
| HDL (mmol/L) | 0.91 (0.70 to 1.12) | 0.3 | – | – |
| Comorbid conditions | ||||
| Heart failure | 1.20 (0.88 to 1.64) | 0.2 | – | – |
| Number of Mix50 Rx | ||||
| 2–5 | 1 | – | – | |
| 6–8 | 0.72 (0.50 to 1.04) | 0.08 | ||
| 9–12 | 0.94 (0.64 to 1.37) | 0.7 | ||
| ≥13 | 1.27 (0.85 to 1.91) | 0.2 | ||
| Duration of therapy (months) | ||||
| 0–3 | 1 | 1 | ||
| 3–6 | 1.64 (0.88 to 3.04) | 0.1 | 1.51 (0.80 to 2.82) | 0.2 |
| 6–9 | 1.90 (1.05 to 3.44) | 0.04 | 1.70 (0.94 to 3.07) | 0.08 |
| 9–12 | 1.95 (1.15 to 3.31) | 0.01 | 1.98 (1.23 to 3.20) | 0.005 |
BMI, body mass index; HDL, high-density lipoprotein; HbA1c; glycated hemoglobin; LRT, likelihood ratio test.