Table 1

Characteristics of cases and controls

VariablesCases (n=116)
Means (95% CI)
n (%)
Controls (n=348)
Means (95% CI)
n (%)
p Value
Demographics
 Age70.8 (68.7 to 72.7)69.4 (68.4 to 70.5)0.20
 Male94 (81)282 (81)
 Lower SES95 (82)272 (78)0.40
 Single46 (40)69 (20)<0.00
 Type 2 diabetes102 (87)301 (87)0.90
Timing of first contact with any secondary healthcare services that manage diabetes
 None or within 1 year prior to event43 (37)154 (44)0.20
 Within 2–3 years prior to event15 (13)51 (15)
 Within 4–7 years prior to event58 (50)143 (41)
Cardiovascular risk factors
 Smoking*55 (47)138 (40)0.10
 Hypertension75 (65)185 (53)0.03
 Obesity14 (12)28 (8)0.20
 Dyslipidemia32 (28)71 (20)0.10
Comorbidities
 CKD46 (40)90 (26)<0.00
 Retinopathy23 (20)106 (30)0.03
 IHD/CVD61 (53)171 (49)0.50
 PVD86 (74)59 (17)<0.00
 Minor LEA32 (28)2 (0.6)<0.00
HbA1c
 1 year prior to event7.6 (7.2 to 8.0)7.6 (7.4 to 7.7)0.80
 3 years prior to event8.7 (8.2 to 9.3)7.9 (7.7 to 8.1)0.01
 5 years prior to event8.8 (8.2 to 9.4)7.9 (7.6 to 8.2)0.01
 7 years prior to event8.9 (8.2 to 9.8)7.9 (7.5 to 8.3)0.01
  • CKD, chronic kidney disease; CVD, cerebrovascular disease; HbA1c, glycated hemoglobin; IHD, ischemic heart disease; LEA, lower extremity amputation; PVD, peripheral vascular disease; SES, socioeconomic status.