Table 6

Renal function at the initial and final stages and its change during the 11-year observation period

CharacteristicCI (n=12)CII (n=14)CIII (n=11)ANOVA
Initial eGFR (mL/min/1.73 m2)88.0±14.993.9±26.193.9±17.2NS
Final eGFR (mL/min/1.73 m2)76.5±24.459.9±21.576.6±13.1NS (0.07)
Slope of eGFR decline (mL/min/1.73 m2/year)−1.08±1.23−4.11±3.99−1.69±1.960.02
p Value (initial vs final eGFR)NS0.00010.0058
Initial ACR25.9 (2.2–277.1)50.9 (7.4–169.8)15.8 (5.6–251.0)NS
Final ACR16.2 (0.2–1403.2)162.8 (2.4–4135.9)44.9 (3.1–367.2)NS
p Value (initial vs final ACR)NS<0.05NS
Initial albuminuria stage (normoalbuminuria/ microalbuminuria/macroalbuminuria)7/5/05/9/07/4/0NS
Final albuminuria stage (normoalbuminuria/ microalbuminuria/macroalbuminuria)7/3/24/4/65/5/1NS
p Value (initial vs final albuminuria stage)NSp<0.05 (χ2=8.0)NS
  • ACR, albumin/creatinine ratio; ANOVA, analysis of variance; CI, category I; CII, category II; CIII, category III; eGFR, estimated glomerular filtration rate; NS, not significant.