Patient characteristics at baseline and the percentage of patients with at least one test in 1 year after initiation of antidiabetic drug therapy and at any time during follow-up
| Characteristics | Number of patients (%) | Number of patients with at least one test in 1 year after cohort entry (%) | p Value for χ2 test for trend | Number of patients with at least one test during any time in the follow-up (%) | Time in months to the first test among patients with at least one test (median, Q1–Q3)* | p Value for trend |
|---|---|---|---|---|---|---|
| N | 65 790 (100) | 49 707 (75.6) | – | 59 400 (90.3) | 4.9 (1.1–11.9) | – |
| Age (years) | ||||||
| 40–49 | 9838 (15.0) | 6836 (69.5) | <0.0001 | 8441 (85.8) | 3.9 (0.8–10.1) | <0.0001 |
| 50–59 | 16 322 (24.8) | 12 127 (74.3) | 14 668 (89.9) | 3.8 (0.7–9.7) | ||
| 60–69 | 19 493 (29.6) | 15 040 (77.2) | 17 921 (91.9) | 4.0 (0.8–9.7) | ||
| 70–79 | 14 321 (21.7) | 11 414 (79.7) | 13 244 (92.5) | 3.9 (0.8–9.1) | ||
| 80+ | 5816 (8.8) | 4290 (73.8) | 5126 (88.1) | 4.4 (1–10) | ||
| Sex | ||||||
| Male | 37 822 (57.5) | 28 714 (75.9) | 0.8849 | 34 321 (90.7) | 3.9 (0.8–9.7) | 0.0145 |
| Female | 27 968 (42.5) | 20 993 (75.1) | 25 079 (89.7) | 4 (0.9–9.7) | ||
| Smoking status | 0.0164 | |||||
| Never | 23 885 (36.3) | 17 905 (75.0) | 21 459 (89.8) | 3.9 (0.8–9.7) | 0.0003 | |
| Current | 11 638 (17.7) | 8566 (73.6) | 10 348 (88.9) | 3.9 (0.8–9.9) | ||
| Former | 28 498 (43.3) | 21 950 (77.0) | 26 081 (91.5) | 4.1 (0.8–9.7) | ||
| Unknown | 1769 (2.7) | 1286 (72.7) | 1512 (85.5) | 3.1 (0.7–8.0) | ||
| Year of cohort entry | <0.0001 | <0.0001 | ||||
| 2007 | 11 959 (18.2) | 9187 (76.8) | 11 288 (94.4) | 4.2 (0.9–10.3) | ||
| 2008 | 12 014 (18.3) | 9287 (77.3) | 11 259 (93.7) | 3.9 (0.8–10.0) | ||
| 2009 | 12 658 (19.2) | 9777 (77.2) | 11 700 (92.4) | 3.8 (0.8–9.6) | ||
| 2010 | 12 306 (18.7) | 9158 (74.4) | 11 043 (89.7) | 4.1 (0.9–9.9) | ||
| 2011 | 11 062 (16.8) | 8066 (72.9) | 9541 (86.3) | 3.9 (0.8–9.6) | ||
| 2012 | 5791 (8.8) | 4232 (73.1) | 4569 (78.9) | 3.5 (0.6–8.0) | ||
| History of hypertension | 0.6154 | 0.8910 | ||||
| No | 29 324 (44.6) | 21 845 (74.5) | 26 078 (88.9) | 3.6 (0.7–9.4) | ||
| Yes | 36 466 (55.4) | 27 862 (76.4) | 33 322 (91.4) | 4.2 (0.9–9.9) | ||
| History of nephropathy† | 0.9610 | <0.0001 | ||||
| No | 57 114 (86.8) | 43 062 (75.4) | 51 461 (90.1) | 3.9 (0.8–9.6) | ||
| Yes | 8676 (13.2) | 6645 (76.6) | 7939 (91.5) | 4.6 (1.0–10.0) |
*Patients’ follow-up time was censored on the date of the first test for proteinuria during follow-up.
†History of diabetic renal complications was defined as a diagnosis of albuminuria, proteinuria, diabetic nephropathy, nephrotic syndrome, chronic renal disease, renal failure, dialysis, or renal transplant at any time before cohort entry date.