Variable | Metformin (n=172) | Control (n=174) | p Value |
---|---|---|---|

Physical diagnostics | |||

Body weight, mean (95% CI), kg | 83.8 (83.0 to 84.7) | 85.2 (84.4 to 86.1) | 0.024 |

Body mass index, mean (95% CI), kg/m^{2} | 26.8 (26.5 to 27.0) | 27.2 (27.0 to 27.5) | 0.014 |

Systolic blood pressure, mean (95% CI), mmHg | 123 (120 to 125) | 125 (122 to 127) | 0.241 |

Diastolic blood pressure, mean (95% CI), mmHg | 74 (72 to 75) | 74 (72 to 75) | 0.649 |

Laboratory values | |||

HbA1c, mean (95% CI), % | 5.83 (5.79 to 5.87) | 5.89 (5.85 to 5.92) | 0.049 |

HbA1c, mean (95% CI), mmol/mol | 40.2 (39.8 to 40.6) | 40.9 (40.4 to 41.2) | 0.049 |

Insulin, mean (95% CI), mU/L | 22.8 (17.5 to 28.1) | 18.6 (13.5 to 23.7) | 0.211 |

Total cholesterol, mean (95% CI), mmol/L | 3.85 (3.73 to 3.97) | 4.02 (3.90 to 4.14) | 0.045 |

LDL cholesterol, mean (95% CI), mmol/L | 2.10 (1.99 to 2.20) | 2.30 (2.20 to 2.40) | 0.007 |

HDL cholesterol, mean (95% CI), mmol/L | 1.20 (1.16 to 1.23) | 1.23 (1.20 to 126) | 0.153 |

Values were calculated using ANCOVA, adjusted for baseline variables.

ANCOVA, analysis of covariance; HbA1c, glycated hemoglobin; HDL, high-density lipoprotein; LDL, low-density lipoprotein.