Table 2

Summary of results from vertex-based shape analysis*

 Structures
Hipp,LHipp,RCaud,LCaud,RPuta,LPuta,RPall,LPall,R
All participants
Positive
 Number of clusters10001200
 Total voxels79000215600
Negative
 Number of clusters33000000
 Total voxels675189000000
Participants with NFG
Positive
 Number of clusters01110100
 Total voxels021296503000
Negative
 Number of clusters20312100
 Total voxels5503371082653300
Participants with diabetes
Positive
 Number of clusters10025200
 Total voxels34007645713900
Negative
 Number of clusters30000000
 Total voxels2840000000
Participants with NFG vs diabetes
Positive
 Number of clusters31100000
 Total voxels206602500000
Negative
 Number of clusters14531132
 Total voxels344374475309081058360506
  • *Summary of results from vertex-based shape analysis of left (L) and right (R) hippocampus (Hipp), caudate (Caud), putamen (Puta) and globus pallidus (Pall), correlating plasma glucose levels with changes of vertex location among all participants, participants with normal fasting plasma glucose levels (NFG) and participants with diabetes, as well as comparing participants with NFG with participants with diabetes. Data were summarized from output of statistically significant clusters at t<−1.96 for negative association and t>1.96 for positive association (p<0.05). Results were adjusted for all covariates (including type 2 diabetes (T2D) diagnosis for groups including all participants). Clusters with size >20 voxels are included in this table.