Adopted therapeutic plan | HbA1c at baseline | HbA1c after 12 months | HbA1c after 48 months | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
N | Mean (SD) | F (df) | p Value | N | Mean (SD) | F (df) | p Value | N | Mean (SD) | F (df) | p Value | |
DPP4i (sitagliptin alone) | 8 | 7.85 (1.28) | 2.63 (7.162) | 0.014 | 4 | 6.15 (0.74) | 4.36 (7.162) | <0.0001 | 5 | 6.44 (0.61) | 6.09 (7.162) | <0.0001 |
DPP4i+metformin | 70 | 8.25 (0.72) | 72 | 7.10 (0.74) | 74 | 7.05 (0.69) | ||||||
DPP4i+metformin+SU | 75 | 8.46 (0.72) | 75 | 7.66 (0.81) | 75 | 7.63 (0.61) | ||||||
DPP4i+metformin+SU+other | 1 | 9.20 (0.00) | 2 | 7.70 (1.41) | 1 | 7.70 (0.00) | ||||||
DPP4i+metformin+other | 4 | 8.70 (0.55) | 4 | 7.43 (0.36) | 4 | 8.08 (0.17) | ||||||
DPP4i+SU | 6 | 8.42 (0.93) | 7 | 7.49 (0.76) | 6 | 6.98 (0.63) | ||||||
DPP4i+SU+other | 1 | 8.60 (0.00) | 1 | 7.60 (0.00) | 1 | 7.90 (0.00) | ||||||
DPP4i+other | 5 | 7.26 (0.97) | 5 | 7.00 (0.91) | 4 | 7.37 (0.23) |
DPP4i, dipeptidyl peptidase-4 inhibitor (sitagliptin); HbA1c, glycated hemoglobin; other, other oral antihyperglycemic agents, or insulin therapy; SU, sulfonylureas.