Overall mortality | Cardiovascular death | Myocardial infarction | |||||||
Variable (effect) | HR | 95% CI | p Value | HR | 95% CI | p Value | HR | 95% CI | p Value |
BMI (direct) | 1.956 | 1.002 to 3.821 | 0.0494 | 1.737 | 0.594 to 5.082 | 0.3133 | 0.317 | 0.133 to 0.756 | 0.0096 |
(indirect) | 0.384 | 0.179 to 0.821 | 0.0136 | 0.145 | 0.028 to 0.750 | 0.0213 | 1.068 | 0.377 to 3.030 | 0.9014 |
HbA1c (direct) | 0.329 | 0.193 to 0.560 | <0.0001 | 0.292 | 0.062 to 1.375 | 0.1195 | 0.488 | 0.230 to 1.037 | 0.0620 |
(indirect) | 1.361 | 0.930 to 1.993 | 0.1123 | 0.988 | 0.350 to 2.789 | 0.9821 | 0.841 | 0.468 to 1.513 | 0.5641 |
SBP (direct) | 0.611 | 0.398 to 0.938 | 0.0241 | 0.263 | 0.051 to 1.358 | 0.1109 | 0.531 | 0.247 to 1.143 | 0.1054 |
(indirect) | 0.948 | 0.672 to 1.339 | 0.7631 | 0.776 | 0.296 to 2.036 | 0.6069 | 0.889 | 0.537 to 1.472 | 0.6479 |
HDL (direct) | 0.493 | 0.280 to 0.868 | 0.0143 | 0.304 | 0.050 to 1.839 | 0.1948 | 0.521 | 0.222 to 1.227 | 0.1358 |
(indirect) | 1.024 | 0.649 to 1.616 | 0.9197 | 0.748 | 0.236 to 2.370 | 0.6222 | 0.681 | 0.383 to 1.211 | 0.1910 |
LDL (direct) | 0.567 | 0.346 to 0.930 | 0.0245 | 0.187 | 0.026 to 1.326 | 0.0935 | 0.347 | 0.156 to 0.772 | 0.0095 |
(indirect) | 1.023 | 0.703 to 1.491 | 0.9041 | 1.664 | 0.553 to 5.010 | 0.3648 | 1.079 | 0.592 to 1.967 | 0.8038 |
BMI, body mass index; HbA1c, hemoglobin A1c; HDL, high-density lipoprotein; LDL, low-density lipoprotein; SBP, systolic blood pressure.