Correlation coefficients between time to closure of the anion gap and admission variables
| Variable | n | Correlation coefficient | p Value | Variable | n | Correlation coefficient | p Value |
| Age (years) | 383 | −0.07887 | 0.11 | BUN (mg/dL) | 383 | −0.00017 | 0.99 |
| Weight (kg) | 307 | −0.06908 | 0.21 | Creatinine (mg/dL) | 383 | −0.07177 | 0.10 |
| BMI | 277 | −0.08167 | 0.16 | Admission serum glucose (mg/dL) | 367 | 0.04744 | 0.35 |
| Initial pH | 279 | 0.09654 | 0.09 | Anion gap (mmol/L) | 383 | −0.08352 | 0.09 |
| BHB (mg/dL) | 283 | −0.02508 | 0.66 | HgbA1c (%) | 309 | −0.03936 | 0.48 |
↵The relationship between the time to closure of the anion gap and admission variables was assessed using the Pearson product–moment correlation. To further compare the times to closure of the anion gap between the two protocols while statistically controlling for the effects of admission variables, an analysis of covariance model was developed using time to closure of the anion gap as the dependent variable, and admission variables as covariates.
BHB, beta-hydroxybutyrate; BMI, body mass index; BUN, blood urea nitrogen; HgbA1c, hemoglobin A1c.