Time point | Weight change (lb) | Weight change (%) | A1c change | |||

Mean (SE)* | p Value | Mean (SE)* | p Value | Mean (SE)* | p Value | |

16 weeks | −11.6 (0.7) | <0.0001 | −5.2 (0.3) | <0.0001 | +0.03 (.06) | 0.62 |

1 year | −10.2 (0.9) | <0.0001 | −4.9 (0.5) | <0.0001 | −0.40 (.07) | <0.0001 |

2 years | −8.3 (1.4) | <0.0001 | −4.3 (0.8) | <0.0001 | −0.46 (.08) | <0.0001 |

3 years | −6.3 (2.1) | 0.0024 | −2.9 (1.0) | 0.0024 | −0.33 (.09) | 0.0005 |

*Adjusted mean and SE values from linear mixed models. At baseline, these participants had an adjusted mean (SE) weight of 219.8 (3.9) lb and an adjusted mean (SE) A1c of 6.02 (0.08).