Table 3

Univariable and multivariable logistic regression model of clinical characteristics associated with incidence of diabetes (n=703)

OR
(95% CI)
Adjusted OR
(95% CI)
Sex at birth
 Female0.73 (0.38 to 1.39)0.53 (0.23 to 1.22)
 Male (ref)1.001.00
Calendar year of first antiretroviral therapy
 1997–19994.11 (2.34 to 7.19)48.90 (21.32 to 112.17)
 2000–20043.57 (2.01 to 6.32)7.22 (3.7 to 14.1)
 2005–2009 (ref)1.001.00
 2010–20150.17 (0.04 to 0.75)0.05 (0.01 to 0.24)
CD4 nadir (per 100 cells/mm3 increase)0.64 (0.53 to 0.78)0.79 (0.61 to 1.02)
Time from antiretroviral therapy initiation to either the date of diabetes diagnosis or the end of study (per year increase)0.94 (0.90 to 0.98)0.69 (0.64 to 0.74)
Proportion of follow-up time with plasma viral load ≥500 copies/mL (per 10% increase)1.12 (1.04 to 1.22)0.93 (0.83 to 1.03)
Proportion of follow-up time on antiretroviral therapy agents (per 10% increase)
 Stavudine1.39 (1.27 to 1.53)Not selected
 Zidovudine1.19 (1.08 to 1.31)
 Lopinavir1.19 (1.11 to 1.28)
 Indinavir1.44 (1.20 to 1.73)
 Saquinavir1.17 (0.94 to 1.46)
 Nelfinavir1.63 (1.19 to 2.24)