Ever exposed to pioglitazone n=31 133 | Never exposed to pioglitazone n=31 133 | |||
N | Mortality rate per 10 000 patient-years (95% CI) | N | Mortality rate per 10 000 patient-years (95% CI) | |
Myocardial infarction | 467 | 57.73 (52.72 to 63.21) | 1380 | 164.78 (156.31 to 173.71) |
Stroke | 92 | 11.37 (9.27 to 13.95) | 340 | 40.6 (36.5 to 45.15) |
Heart failure | 47 | 5.81 (4.37 to 7.73) | 132 | 15.76 (13.29 to 18.69) |
Peripheral vascular disease | 15 | 1.85 (1.12 to 3.08) | 33 | 3.94 (2.8 to 5.54) |
Arrhythmia | 9 | 1.11 (0.58 to 2.14) | 42 | 5.01 (3.71 to 6.79) |
Renovascular disease | 1 | 0.12 (0.02 to 0.88) | 12 | 1.43 (0.81 to 2.52) |
Sudden death* | 0 | 2 | ||
Other cardiovascular diseases of interest | 60 | 7.42 (5.76 to 9.55) | 157 | 18.75 (16.03 to 21.92) |
*Mortality not calculated due to lack of statistical convergence of the model.