CCHC | PURSE | |||||||
Overall (n=3023) | DM (n=826) | No DM (n=2197) | Difference (95% CI) | Overall (n=8080) | DM (n=2207) | No DM (n=5873) | Difference (95% CI) | |
Continuous variables* | ||||||||
Age | 47.3 (16.1) | 54.3 (11.2) | 44.8 (16.8) | 9.5 (5.3 to 13.7) | 43.8 (10.3) | 48.9 (9.2) | 41.9 (10.0) | 7.0 (6.3 to 7.8) |
Body mass index | 31.5 (6.3) | 34.8 (7.0) | 30.3 (5.6) | 4.5 (2.5 to 6.4) | 24.8 (4.6) | 26.1 (4.4) | 24.3 (4.6) | 1.7 (1.4 to 2.1) |
Waist circumference | 104.9 (15.4) | 114.3 (16.6) | 101.6 (13.5) | 12.7 (8.0 to 17.4) | 83.5 (10.7) | 88.1 (9.4) | 81.8 (10.7) | 6.2 (5.5 to 7.0) |
Hip circumference | 111.1 (13.0) | 116.4 (15.5) | 109.2 (11.4) | 7.2 (11.8 to 2.5) | 94.0 (10.5) | 97.1 (9.8) | 92.8 (10.6) | 5.3 (3.6 to 5.0) |
Waist-to-hip ratio | 0.9 (0.1) | 1.0 (0.1) | 0.9 (0.1) | 0.1 (0.0 to 0.1) | 0.9 (0.1) | 0.9 (0.1) | 0.9 (0.1) | 0.02 (0.02 to 0.03) |
Fasting blood glucose | 109.3 (39.9) | 149.7 (60.4) | 94.9 (8.3) | 54.8 (35.3 to 74.2) | 107.4 (41.8) | 147.9 (62.1) | 92.0 (8.7) | 55.9 (52.8 to 59.0) |
HbA1c % | 6.2 (1.6) | 8.0 (1.9) | 5.5 (0.5) | 2.5 (2.0 to 3.0) | 6.3 (1.6) | 8.1 (2.0) | 5.7 (0.4) | 2.5 (2.4 to 2.6) |
Insulin | 14.5 (12.3) | 16.7 (14.0) | 13.7 (11.5) | 3.1 (−1.6 to 7.7) | 8.5 (7.3) | 9.6 (6.7) | 8.0 (7.5) | 1.6 (1.2 to 2.0) |
HOMA-IR | 4.0 (4.0) | 6.1 (5.5) | 3.2 (3.0) | 2.8 (1.0 to 4.7) | 2.3 (2.2) | 3.4 (2.8) | 1.8 (1.7) | 1.6 (1.4 to 1.7) |
Total cholesterol | 185.2 (37.0) | 172.3 (41.8) | 189.8 (34.0) | −17.5 (−31.5 to 3.5) | 177.5 (39.2) | 186.3 (41.5) | 174.1 (37.8) | 12.2 (9.7 to 14.6) |
HDL | 48.7 (11.5) | 44.6 (10.9) | 50.1 (11.6) | −5.6 (−9.0 to 2.1) | 42.3 (9.3) | 41.6 (9.4) | 42.6 (9.3) | −1.0 (−1.6 to 0.4) |
LDL (calculated) | 108.7 (31.4) | 97.1 (37.8) | 112.7 (28.7) | −15.6 (−26.7 to 4.4) | 114.7 (48.3) | 120.1 (56.8) | 112.7 (44.6) | 7.4 (5.4 to 9.4) |
Triglycerides | 143.6 (94.7) | 158.6 (125.1) | 138.3 (80.4) | 20.2 (9.1 to 49.5) | 134.2 (95.7) | 167.1 (133.9) | 121.7 (72.4) | 45.5 (38.0 to 53.0) |
AST | 27.5 (16.6) | 27.5 (18.5) | 27.5 (15.8) | 0.0 (−4.6 to 4.5) | 24.0 (21.7) | 23.9 (15.7) | 24.1 (23.5) | −0.1 (−1.2 to 0.9) |
ALT | 32.8 (23.2) | 33.5 (23.2) | 32.6 (23.2) | 0.9 (−5.8 to 7.5) | 40.4 (17.7) | 42.5 (17.5) | 39.7 (17.6) | 2.9 (1.9 to 3.9) |
AST/ALT ratio | 1.0 (0.4) | 0.9 (0.3) | 1.0 (0.4) | −0.1 (−0.2 to 0.0) | 0.6 (0.2) | 0.6 (0.2) | 0.6 (0.2) | −0.0 (−0.1 to 0.0) |
Systolic blood pressure | 125.3 (20.0) | 131.6 (22.8) | 123.1 (18.4) | 8.5 (1.9 to 15.2) | 121.4 (19.0) | 127.4 (19.6) | 119.2 (18.3) | 8.2 (7.1 to 9.3) |
Diastolic blood pressure | 76.8 (8.5) | 77.7 (9.4) | 76.8 (8.1) | 1.2 (−1.1 to 3.5) | 76.2 (10.8) | 78.5 (10.6) | 75.3 (10.8) | 3.3 (2.6 to 3.9) |