Table 3

Multiple linear regression model predicting 1-year glycated hemoglobin A1c (HbA1c) change as a function of medication possession ratio (MPR), stratified by oral antihyperglycemic agent (OHA) therapy cohort

Multivariate model
ValueSEt-valuep-value
OHA monotherapy
Change in HbA1c (%)
 MPR (%)−0.8920.076−11.6800.000
 Constant−0.0020.073−0.0300.974
MPR (%)
 Age (years)0.0020.00010.1100.000
 Change in BMI (kg/m2)−0.0030.001−2.7600.006
 Baseline HbA1c (%)−0.0020.002−1.4000.162
 Change in total cholesterol−0.0160.002−7.2700.000
 Constant0.8270.01942.7800.000
OHA dual therapy
Change in HbA1c (%)
 MPR (%)−0.8590.155−5.5500.000
 Constant−0.1330.143−0.9300.353
MPR (%)
 Age (years)0.0020.0006.3200.000
 Change in BMI (kg/m2)0.0040.0012.4200.015
 Baseline HbA1c (%)−0.0070.002−3.4000.001
 Change in total cholesterol−0.0120.003−4.2300.000
 Constant0.8740.02337.3000.000
OHA triple therapy
Change in HbA1c (%)
 MPR (%)−2.0580.348−5.9200.000
 Constant0.8400.3192.6300.009
MPR (%)
 Age (years)0.0010.0012.1700.031
 Change in BMI (kg/m2)−0.0010.004−0.2200.823
 Baseline HbA1c (%)−0.0130.005−2.6100.009
 Change in total cholesterol−0.0160.008−1.9300.054
 Constant0.9410.06315.0500.000
  • BMI, body mass index.