Table 1

Anthropometry, body composition and energy expenditure by parental diabetes

CharacteristicsAll subjects (n=170)No parental diabetes (n=83)Parental diabetes (n=87)Mean difference (95% CI) or OR (95% CI)P value
(no parental vs parental diabetes)
Age (years)38.8±11.337.7±12.739.9±9.7−2.2 (−5.7 to 1.2)0.1956
BMI (kg/m2)28.5±6.128.2±5.928.8±6.3−0.6 (−2.4 to 1.3)0.5473
(F/M)97/7347/3650/370.97 (0.53 to 1.77)0.9114
Ethnicity (C/AA)80/9040/4340/471.09 (0.60 to 2.00)0.7723
Weight (kg)83.9±20.382.5±19.685.2±20.8−2.7 (−8.8 to 3.5)0.3924
Waist circumference (cm)91.8±15.190.3±15.593.2±14.7−2.9 (−7.5 to 1.7)0.2187
Fat-free mass (kg)54.4±12.953.8±12.655.0±13.21.2 (−5.1 to 2.7)0.5343
% body fat31.0±10.030.3±10.731.6±9.3−1.3 (−4.4 to 1.7)0.3905
Fasting blood glucose (mg/dL)89.8±6.289.4±6.590.3±5.9−0.9 (−2.7 to 1.0)0.3537
2 hours postglucose (mg/dL)119.1±25.7112.8±18.6125.0±30.0−12.2 (−19.7 to to 4.7)0.0018
HOMA-IR1.30±1.410.94±0.861.65±1.71−0.71 (−1.12 to to 0.29)0.0009
HOMA-B (%)75.9±66.857.1±42.993.8±79.7−36.7 (−56.2 to to 17.1)0.0003
REE (Kcal/day)1645.3±433.81705.8±484.91587.6±372.5118.1 (−13.3 to 249.6)0.0759
Normalized REE (Kcal/day)1425.4±299.81489.4±323.21364.4±263.4124.9 (35.9 to 214.0)0.0063
REE/FFM (Kcal/kg FFM/day)30.5±5.831.9±6.029.2±5.32.7 (1.0 to 4.4)0.0020
  • AA, African-American; C, Caucasian; BMI, body mass index; F, female; FFM, fat-free mass; HOMA-B, homeostatic model assessment of beta-cell function; HOMA-IR, homeostatic model assessment of insulin resistance; M, male; REE, resting energy expenditure.