Baseline characteristics
| Total n=81 233 | Insomnia n=24 146 | No insomnia n=57 087 | P value | |
| Age | <0.0001 | |||
| Mean (SD) | 57.5 (13.6) | 58.4 (13.1) | 57.1 (13.8) | |
| BMI, kg/m2, n (%) | <0.0001 | |||
| <25 | 14 238 (17.5) | 4013 (16.6) | 10 225 (17.9) | |
| ≥25 to 29.9 | 26 694 (32.9) | 7417 (30.7) | 19 277 (33.8) | |
| ≥30 to 39.9 | 31 943 (39.3) | 9699 (40.2) | 22 244 (39.0) | |
| ≥40 | 358 (10.3) | 3017 (12.5) | 5341 (9.4) | |
| Sex, n (%) | <0.0001 | |||
| Female | 43 562 (53.6) | 13 547 (56.1) | 30 015 (52.6) | |
| Male | 37 671 (46.4) | 10 599 (43.9) | 27 072 (47.4) | |
| Race, n (%) | <0.0001 | |||
| White | 65 803 (81.0) | 20 761 (86.0) | 45 042 (78.9) | |
| Asian | 3979 (4.9) | 724 (3.0) | 3255 (5.7) | |
| Black | 2208 (2.7) | 572 (2.4) | 1636 (2.9) | |
| Other | 9243 (11.4) | 2089 (8.7) | 7154 (12.5) | |
| Ethnicity, n (%) | <0.0001 | |||
| Not Hispanic | 76 946 (94.7) | 23 176 (96.0) | 23 176 (94.2) | |
| Hispanic | 4287 (5.3) | 970 (4.0) | 3317 (5.8) | |
| Smoking status, n (%) | <0.0001 | |||
| Never | 43 202 (53.2) | 11 778 (48.8) | 31 424 (55.0) | |
| Current | 10 063 (12.4) | 3172 (13.1) | 6891 (12.1) | |
| Previous | 27 519 (33.9) | 9084 (37.6) | 18 435 (32.3) | |
| Unknown | 449 (0.6) | 112 (0.5) | 337 (0.6) | |
| Congestive heart failure, n (%) | <0.0001 | |||
| No | 79 915 (98.4) | 23 613 (97.8) | 56 302 (98.6) | |
| Yes | 1318 (1.6) | 533 (2.2) | 785 (1.4) | |
| Myocardial infarction, n (%) | 0.07 | |||
| No | 80 639 (99.3) | 23 949 (99.2) | 56 690 (99.3) | |
| Yes | 594 (0.7) | 197 (0.8) | 397 (0.7) | |
| Hypertension, n (%) | <0.0001 | |||
| No | 35 159 (43.3) | 9346 (38.7) | 25 813 (45.2) | |
| Yes | 46 074 (56.7) | 14 800 (61.3) | 31 274 (54.8) | |
| Elevated triglycerides (≥150 mg/dL), n (%) | <0.0001 | |||
| No | 38 478 (47.4) | 10 976 (45.5) | 27 502 (48.2) | |
| Yes | 42 755 (52.6) | 13 170 (54.5) | 29 858 (51.8) | |
| Low HDL (<40 mg/dL), n (%) | <0.0001 | |||
| No | 4929 (60.7) | 14 166 (58.7) | 35 128 (61.5) | |
| Yes | 31 939 (39.3) | 9980 (41.3) | 21 959 (38.5) | |
| Hemoglobin A1c | n=45 261 | n=12 485 | n=32 776 | <0.0001 |
| %, mean (SD) | 5.8 (0.25) | 5.8 (0.26) | 5.9 (0.25) | |
| mmol/mol, mean (SD) | 40 (2.73) | 40 (2.84) | 41 (2.73) | |
| Fasting glucose | n=50 443 | n=16 714 | n=33 729 | 0.87 |
| mg/dL, mean (SD) | 102.4 (9.62) | 102.4 (9.45) | 102.4 (9.70) |
BMI, body mass index; HDL, high-density lipoprotein.