Table 4

Comparison of change in HOMA2-%β and HOMA2-%S before and after selenium supplementation, stratified by sex and age

NAverageSDMaxMinP value
HOMA2-%β
FemalePlacebo57−2.717.230.9−56.40.08*
Selenium734.023.6102.3−61.0
MalePlacebo1315.633.6202.6−67.20.41
Selenium1282.524.390.3−65.0
Age <63Placebo871.833.3202.6−67.20.86
Selenium952.624.290.3−65.0
Age ≥63Placebo1014.226.5161.7−52.20.84
Selenium1063.523.9102.3−61.0
HOMA2-%S
FemalePlacebo57−58.6631.72173.5−4102.80.53†
Selenium73−4.3194.9656.0−707.1
MalePlacebo131141.61785.220 345.5−731.50.50
Selenium1281.7238.61483.6−1165.7
Age <63Placebo87170.72235.420 345.5−4102.80.99
Selenium952.0288.11483.6−1165.7
Age ≥63Placebo1013.6268.12173.5−731.50.21
Selenium106−2.8143.5427.8−707.1
  • *Student’s t-test.

  • †Kruskal-Wallis test.

  • HOMA2-%β, homeostatic model assessment of β-cell function; HOMA2-%S, homeostatic model assessment of insulin sensitivity.