Table 2

Availability of data used to assess the eligibility of patients in the DISCOVER study for CANVAS, DECLARE-TIMI 58, EMPA-REG OUTCOME, and VERTIS-CV, overall and by region

OverallAsia-PacificEuropeLatin AmericaMiddle East and Africa
N=15 992n=7517n=2943n=1616n=3530
Age15 992 (100.0)7517 (100.0)2943 (100.0)1616 (100.0)3530 (100.0)
Sex15 988 (100.0)7517 (100.0)2939 (99.9)1616 (100.0)3530 (100.0)
HbA1c12 784 (79.9)5738 (73.4)2506 (85.2)125 (77.4)3009 (85.2)
BMI14 757 (92.3)7084 (94.2)2747 (93.3)1251 (77.4)3126 (88.6)
Smoking status15 600 (97.5)7362 (97.9)2843 (96.6)1584 (98.0)3431 (97.2)
Information on comedication use15 992 (100.0)7517 (100.0)2943 (100.0)1616 (100.0)3530 (100.0)
Information on comorbidities*
 Hypertension15 971 (99.9)7517 (100.0)2922 (99.3)1616 (100.0)3530 (100.0)
 Hyperlipidemia15 971 (99.9)7517 (100.0)2922 (99.3)1616 (100.0)3530 (100.0)
 CKD15 971 (99.9)7517 (100.0)2922 (99.3)1616 (100.0)3530 (100.0)
 CVD†15 947 (99.7)7517 (100.0)2898 (98.5)1616 (100.0)3530 (100.0)
eGFR8782 (54.9)4267 (56.8)1754 (59.6)732 (45.3)2013 (57.0)
LDL-C8765 (54.8)4226 (56.2)1693 (57.5)715 (44.2)1871 (53.0)
HDL-C8786 (54.9)4150 (55.2)1739 (59.1)792 (49.0)1833 (51.9)
SBP15 252 (95.4)7299 (97.1)2778 (94.4)1539 (95.2)3259 (92.3)
DBP15 239 (95.3)7289 (97.0)2778 (94.4)1539 (95.2)3256 (92.2)
Patients included in the analysis‡11 385 (71.2)5206 (69.2)2174 (73.9)1161 (71.8)2624 (74.3)
  • Data are reported as n (%) for patients with available data.

  • *Marked as present or not present by the investigator in the electronic case report form.

  • †Composite of coronary heart disease, cerebrovascular disease, peripheral artery disease, heart failure, and implantable cardioverter defibrillator use.

  • ‡Patients with available information on age, sex, HbA1c, BMI, smoking status, comedication use, and comorbidities.

  • BMI, body mass index;CKD, chronic kidney disease;CVD, cardiovascular disease;DBP, diastolic blood pressure;eGFR, estimated glomerular filtration rate;HbA1c, glycated hemoglobin;HDL-C, high-density lipoprotein cholesterol;LDL-C, low-density lipoprotein cholesterol;SBP, systolic blood pressure.