Characteristics | 2014* | 2015 | P value | 2016 | P value | 2017 | P value | 2018† | P value |
Number of DKA (n) | 77 | 107 | 110 | 114 | 24 | ||||
Age (years) | 34 (20–51) | 34 (21–58) | 34 (21–58) | 46 (24–59) | 29 (19.5–50.5) | ||||
Male gender (%) | 48.1 | 55.1 | 33.6 | 48.2 | 50.0 | ||||
Body weight (kg) | 63.9 (55.8–76.7) | 65.0 (60.0–74.4) | 0.29 | 64.0 (56.5–78.0) | 0.76 | 68 (57.2–80.0) | 0.32 | 63.0 (57.1–68.0) | 0.71 |
New type 1 diagnosis (n) | 8 | 8 | 0.49 | 9 | 0.02 | 14 | 0.69 | 5 | 0.2 |
Duration of DKA (Hours) | 21.9 (15.2–38.2) | 10.9 (7.1–15.7) | <0.01 | 9.1 (6.7–17.1) | <0.01 | 14.9 (8.6–24.1) | <0.01 | 15.7 (11.8–24.7) | 0.05 |
Appropriateness of FRIII prescription (% difference) | −1.3 (−9.1 to 2.9) | −0.7 (−7.4 to 2.8) | 0.48 | −1.3 (−7.9 to 3.4) | 0.62 | 0 (−4.9 to 4.5) | 0.06 | 0 (−4.05 to 5.2) | 0.22 |
Appropriateness of fluid prescription (% difference) | −20 (−30.0 to 10.0) | 0 (−20.0 to 35.4) | 0.02 | 0 (−25.0 to 25.0) | 0.03 | 12.5 (−12.5 to 50.0) | <0.01 | −25 (−50.0 to 12.5) | 0.19 |
Appropriateness of glucose monitoring (% difference) | 25.0 (08.3–46.3) | 2.8 (−16.7 to 33.3) | 0.03 | 0.5 (−16.7 to 39.8) | <0.01 | 15.0 (−10.0 to 30.0) | 0.13 | 10.0 (−10.0 to 45.0) | 0.47 |
Appropriateness of ketone monitoring (% difference) | −45.0 (−59.6 to −26.5) | −52.4 (−67.4 to −25) | 0.42 | −25.7 (−59.1 to 25) | 0.01 | 75.0 (−25 to 125) | <0.01 | 37.5 (0–100) | <0.01 |
The results are expressed in median (IQR) where appropriate. P values, describing comparison with 2014 preintervention year, were calculated using a Wilcoxon sum rank for non-parametric data and chi-square for categorical data. Statistical significance was set at p<0.05. Significant results are highlighted in bold.
*Patients were included from 1 April 2014 to 31 December 2014.
†Patients were included from 1 January 2018 to 30 September 2018.
DKA, diabetic ketoacidosis.