Table 2

Descriptive characteristics of patients with DFCs

Year20072008200920102011201220132014P for trend
Age (mean, SD)65.33±12.8465.84±13.0565.83±13.1965.92±13.3466.27±13.4266.33±13.4766.06±13.5866.30±13.63
Age≥60 years15 305 (66.4)17 483 (67.1)18 352 (67.1)19 356 (67.4)20 431 (68.6)20 762 (69.2)20 713 (68.3)21 276 (69.1)0.003
Male gender (N, %)12 511(54.2)14 387(55.3)15 271(55.8)16 055(55.9)16 616(55.8)16 991(56.6)17 320(57.1)17 584(57.1)<0.001
Comorbidities (N, %)
 Hypertension15 873(68.8)18 232(70.0)19 494(71.2)20 409(71.0)21 673(72.8)21 874(72.9)22 076(72.8)22 476(73.0)0.001
 Dyslipidemia7960(34.5)9025(34.7)9781(35.7)10 570(36.8)11 371(38.2)11 593(38.6)12 419(40.9)13 067(42.5)<0.001
 Diabetic nephropathy3286(14.2)3812(14.6)4118(15.1)4667(16.2)4963(16.7)5187(17.3)5157(17.0)5258(17.1)0.001
 End-stage renal disease1128(4.9)1435(5.5)1735(6.3)2103(7.3)2376(8.0)2421(8.1)2375(7.8)2382(7.7)0.008
 Diabetic retinopathy452(2.0)520(2.0)502(1.8)540(1.9)507(1.7)497(1.7)403(1.3)377(1.2)0.001
 Diabetic neuropathy1005(4.4)991(3.8)1035(3.8)1064(3.7)1045(3.5)1045(3.5)949(3.1)960(3.1)<0.001
 Coronary heart disease1309(5.7)1492(5.7)1510(5.5)1551(5.4)1739(5.8)1669(5.6)1784(5.9)1728(5.6)0.667
 Heart failure740(3.2)824(3.2)920(3.4)1034(3.6)1065(3.6)1075(3.6)969(3.2)924(3.0)0.763
 Ischemic stroke397(1.7)493(1.9)457(1.7)490(1.7)495(1.7)462(1.5)450(1.5)417(1.4)0.003
 Hemorrhagic stroke21(0.1)36(0.1)35(0.1)44(0.2)31(0.1)49(0.2)29(0.1)31(0.1)0.740
 MACEs*2467(10.7)2845(10.9)2922(10.7)3119(10.9)3330(11.2)3255(10.9)3232(10.7)3100(10.1)0.250
  • *MACEs: including coronary heart disease, heart failure, ischemic stroke and hemorrhagic stroke.

  • DFC, diabetic foot complication; MACE, major adverse cardiac event; N, number of patients.