Table 1

Baseline patient characteristics in the OSA versus non-OSA groups according to diabetes status

VariablesAll (n=804)Diabetes (n=248)No diabetes (n=556)
OSA (n=121)Non-OSA (n=127)P valueOSA (n=282)Non-OSA (n=274)P value
Demographics
 Age, years57.5±10.259.4±9.658.7±9.70.5456.9±10.456.5±10.30.64
 Male664 (82.6)91 (75.2)97 (76.4)0.83251 (89.0)225 (82.1)0.02
 BMI, kg/m226.7±3.627.4±3.026.1±3.10.00127.7±3.725.6±3.5<0.001
 Waist-to-hip ratio0.98 (0.96 to 1.02)0.99 (0.96 to 1.03)0.98 (0.95 to 1.01)0.0090.99 (0.96 to 1.02)0.98 (0.93 to 1.01)0.001
 Neck circumference, cm40 (38 to 42)41 (39 to 43)40 (38 to 42)0.00341 (39 to 43)39 (37 to 41)<0.001
Medical history
 Hypertension530 (65.9)92 (76.0)95 (74.8)0.82183 (64.9)160 (58.4)0.12
 Hyperlipidemia210 (26.1)43 (35.5)41 (32.3)0.5964 (22.7)62 (22.6)0.99
 Prior stroke76 (9.5)20 (16.5)17 (13.4)0.4921 (7.4)18 (6.6)0.69
 Prior myocardial infarction118 (14.7)20 (16.5)22 (17.3)0.8741 (14.5)35 (12.8)0.55
 Prior PCI141 (17.5)27 (22.3)24 (18.9)0.5156 (19.9)34 (12.4)0.02
 Prior CABG11 (1.4)6 (5.0)2 (1.6)0.163 (1.1)0 (0.0)0.25
 Smoking0.440.79
  No288 (35.8)56 (46.3)49 (38.6)89 (31.6)94 (34.3)
  Current406 (50.5)49 (40.5)61 (48.0)153 (54.3)143 (52.2)
  Previous110 (13.7)16 (13.2)17 (13.4)40 (14.2)37 (13.5)
Baseline tests
 Glucose, mmol/L5.9 (5.3 to 7.3)8.5 (6.8 to 11.0)7.4 (6.2 to 9.3)0.0085.7 (5.2 to 6.3)5.5 (5.1 to 6.1)0.07
 Hemoglobin A1c, %6.0 (5.6 to 6.9)7.8 (6.7 to 9.2)7.2 (6.4 to 8.4)0.0065.8 (5.5 to 6.1)5.7 (5.4 to 6.1)0.02
 Hs-CRP, mg/L2.3 (0.8 to 8.6)2.7 (1.0 to 8.9)1.7 (0.7 to 4.8)0.033.0 (1.1 to 11.6)1.9 (0.6 to 6.8)0.001
 LVEF, %60 (55 to 65)60 (55 to 65)63 (57 to 66)0.1460 (56 to 65)60 (55 to 65)0.92
Diagnosis0.200.31
 Unstable angina347 (43.2)59 (48.8)66 (52.0)120 (42.6)102 (37.2)
 NSTEMI203 (25.2)25 (20.7)34 (26.8)66 (23.4)78 (28.5)
 STEMI254 (31.6)37 (30.6)27 (21.3)96 (34.0)94 (34.3)
Procedures
 Coronary angiography786 (97.8)119 (98.3)123 (96.9)0.68278 (98.6)266 (97.1)0.22
 Multivessel disease61.2 (481/786)88/119 (73.9)69/123 (56.1)0.004177/278 (63.7)147/266 (55.3)0.046
 PCI490 (60.9)74 (61.2)66 (52.0)0.15188 (66.7)163 (59.5)0.08
 CABG80 (10.0)14 (11.6)17 (13.4)0.6723 (8.2)26 (9.5)0.58
Medications on discharge
 Aspirin754 (93.8)112 (92.6)116 (91.3)0.72269 (95.4)257 (93.8)0.41
 Thienopyridine720 (89.6)107 (88.4)111 (87.4)0.80262 (92.9)240 (87.6)0.03
 β-blockers611 (76.0)91 (75.2)97 (76.4)0.83222 (78.7)201 (73.4)0.14
 ACEIs/ARBs564 (70.1)83 (68.6)96 (75.6)0.22208 (73.8)177 (64.6)0.02
 Statins762 (94.8)114 (94.2)116 (91.3)0.38271 (96.1)261 (95.3)0.63
  • Data are presented as mean±SD, median (IQR), n (%), or n/N (%).

  • ACEI, ACE inhibitor; ARB, angiotensin receptor blocker; BMI, body mass index; CABG, coronary artery bypass grafting; Hs-CRP, high-sensitivity C reactive protein; LVEF, left ventricular ejection fraction; NSTEMI, non-ST segment elevation myocardial infarction; OSA, obstructive sleep apnea; PCI, percutaneous coronary intervention; STEMI, ST segment elevation myocardial infarction.