Table 4

Comparisons between UKPDS-CHD (CHD=coronary heart disease) (A) and Framingham risk scores (B) with and without the addition of microalbuminuria (no/yes), diabetic retinopathy (DR) (no/yes), DR+microalbuminuria, moderate–severe DR, and moderate–severe DR+microalbuminuria in assessing the presence of the combined endpoint

A
ROC areaSE95% CIP value
UKPDS-CHD0.6580.0440.58 to 0.75
UKPDS-CHD+microalbuminuria0.6830.0440.60 to 0.770.191
UKPDS-CHD+DR0.6870.0450.60 to 0.770.198
UKPDS-CHD+microalbuminuria and DR0.7010.0440.62 to 0.790.074
UKPDS-CHD+moderate–severe DR0.7290.0410.65 to 0.8180.001
UKPDS-CHD+microalbuminuria and moderate–severe DR0.7330.0420.65 to 0.820.008
B
Framingham0.6490.0450.56 to 0.78
Framingham+microalbuminuria0.660.0450.57 to 0.750.52
Framingham+DR0.6780.0460.59 to 0.770.269
Framingham+microalbuminuria and DR0.6830.0450.60 to 0.770.223
Framingham+moderate–severe DR0.7170.0420.67 to 0.830.007
Framingham+microalbuminuria and moderate–severe DR0.7140.0430.63 to 0.800.034
  • UKPDS, United Kingdom Prospective Diabetes Study.