Associations of CKD with distal peripheral neuropathy
| CKD (n=81) | Controls (n=24) | P value* | Adjusted difference (95% CI)† | Adjusted OR (95% CI)† | |
| Mean MNSI questionnaire score | 3.36 (2.97) | 2.33 (2.41) | 0.046 | 1.35 (0.03 to 2.67) | |
| MNSI score ≥2‡ | 51 (63%) | 11 (46%) | 0.160 | 2.29 (0.88 to 6.00) | |
| MNSI score ≥2 or use of one or more neuropathy medications | 56 (69%) | 13 (54%) | 0.222 | 2.31 (0.86 to 6.20) | |
| MNSI score ≥4 | 36 (44%) | 8 (33%) | 0.358 | 2.16 (0.78 to 5.94) |
*Unadjusted t-test or χ2 test.
†Adjusted for age, gender, race
‡ Primary outcome of interest.
CKD, chronic kidney disease; MNSI, Michigan Neuropathy Screening Instrument.