Table 3

Demographics of patients with diabetes by ERFD* status

Non-ERFD (n=417)ERFD (n=417)P value†
Gender
 Male258 (61.9%)257 (61.6%)
 Female159 (38.1%)160 (38.4%)0.943
Age (years)56.15 (10.58)57.99 (9.99)0.010‡
DM duration (years)8.32 (7.23)8.97 (6.39)0.225
Follow-up duration (years)2.86 (2.16)1.24 (1.10)<0.001§
BMI (kg/m2)26.04 (3.67)26.22 (3.86)0.501
HbA1c (%)7.32 (1.53)7.48 (1.31)0.110
SBP (mm Hg)129.58 (19.56)135.39 (18.33)<0.001§
DBP (mm Hg)79.08 (13.00)82.91 (11.60)<0.001§
HDL (mg/dL)49.88 (12.86)48.09 (13.93)0.054
LDL (mg/dL)115.63 (34.70)105.16 (32.72)<0.001§
eGFR (mL/min/1.73 m2)88.70 (28.09)90.52 (28.20)0.352
Urine creatinine (mg/dL)141.68 (91.63)120.52 (72.73)0.001‡
ACR (mg/g)96.12 (353.09)157.47 (472.41)0.046*
  • Values are presented as N (%) or mean±SD.

  • *Early renal function decline was defined as >3.3 mL/min/1.73 m2 decline in the eGFR per year.

  • †P value for χ2 test or two independent t-tests.

  • ‡Represents a p value <0.05.

  • §Represents a p value <0.001.

  • ACR, albumin-to-creatinine ratio; BMI, body mass index; DBP, diastolic blood pressure; DM, diabetes mellitus; eGFR, estimated glomerular filtration rate; ERFD, early renal functional decline; HbA1c, hemoglobin A1c; HDL, high-density lipoprotein; LDL, low-density lipoprotein; SBP, systolic blood pressure.