Demographics of patients with diabetes by ERFD* status
| Non-ERFD (n=417) | ERFD (n=417) | P value† | |
| Gender | |||
| Male | 258 (61.9%) | 257 (61.6%) | |
| Female | 159 (38.1%) | 160 (38.4%) | 0.943 |
| Age (years) | 56.15 (10.58) | 57.99 (9.99) | 0.010‡ |
| DM duration (years) | 8.32 (7.23) | 8.97 (6.39) | 0.225 |
| Follow-up duration (years) | 2.86 (2.16) | 1.24 (1.10) | <0.001§ |
| BMI (kg/m2) | 26.04 (3.67) | 26.22 (3.86) | 0.501 |
| HbA1c (%) | 7.32 (1.53) | 7.48 (1.31) | 0.110 |
| SBP (mm Hg) | 129.58 (19.56) | 135.39 (18.33) | <0.001§ |
| DBP (mm Hg) | 79.08 (13.00) | 82.91 (11.60) | <0.001§ |
| HDL (mg/dL) | 49.88 (12.86) | 48.09 (13.93) | 0.054 |
| LDL (mg/dL) | 115.63 (34.70) | 105.16 (32.72) | <0.001§ |
| eGFR (mL/min/1.73 m2) | 88.70 (28.09) | 90.52 (28.20) | 0.352 |
| Urine creatinine (mg/dL) | 141.68 (91.63) | 120.52 (72.73) | 0.001‡ |
| ACR (mg/g) | 96.12 (353.09) | 157.47 (472.41) | 0.046* |
Values are presented as N (%) or mean±SD.
*Early renal function decline was defined as >3.3 mL/min/1.73 m2 decline in the eGFR per year.
†P value for χ2 test or two independent t-tests.
‡Represents a p value <0.05.
§Represents a p value <0.001.
ACR, albumin-to-creatinine ratio; BMI, body mass index; DBP, diastolic blood pressure; DM, diabetes mellitus; eGFR, estimated glomerular filtration rate; ERFD, early renal functional decline; HbA1c, hemoglobin A1c; HDL, high-density lipoprotein; LDL, low-density lipoprotein; SBP, systolic blood pressure.