Table 1

Logistic regression model comparing the prevalence of macrovascular, microvascular and kidney complications in individuals at high, intermediate or low (reference category) probability of liver fibrosis or steatosis

	Cardiovascular event			eGFR EPI-CKD (cut-off 60)			Microalbuminuria			Diabetic retinopathy
	OR	95% CI	P value	OR	95% CI	P value	OR	95% CI	P value	OR	95% CI	P value
FLI
Low	1	-	-	1	-	-	1	-	-	1	-	-
Middle	1.65	1.13 to 2.40	0.009	1.65	1.03 to 2.68	0.038	2.91	1.65 to 5.14	<0.001	0.83	0.46 to 1.50	0.542
High	1.32	0.94 to 1.85	0.110	1.77	1.15 to 2.72	0.010	3.49	2.05 to 5.94	<0.001	1.05	0.63 to 1.76	0.858
HSI
Low	1	-	-	1	-	-	1	-	-	1	-	-
Middle	4.89	0.50 to 47.61	0.171	1.51	0.15 to 14.78	0.725	-	-	0.999	-	-	0.999
High	0.92	0.73 to 1.18	0.518	0.61	0.47 to 0.84	0.002	0.95	0.68 to 1.35	0.762	0.825	0.54 to 1.31	0.408
NAFLD Ridge Score
Low	1	-	-	1	-	-	1	-	-	1	-	-
Middle	0.52	0.25 to 1.15	0.108	0.51	0.22 to 1.17	0.110	1.20	0.39 to 3.68	0.750	0.99	0.24 to 4.10	0.986
High	0.95	0.48 to 1.89	0.894	0.57	0.28 to 1.16	0.118	1.79	0.67 to 4.81	0.248	1.50	0.44 to 5.13	0.520
AST/ALT
Low	1	-	-	1	-	-	1	-	-	1	-	-
Middle	1.73	1.42 to 2.10	<0.001	2.04	1.59 to 2.60	<0.001	0.94	0.73 to 1.20	0.594	1.58	1.09 to 2.27	0.015
High	1.86	1.37 to 2.54	<0.001	3.76	2.67 to 5.31	<0.001	1.40	0.95 to 2.06	0.090	2.68	1.61 to 4.48	<0.001
APRI
Low	1	-	-	1	-	-	1	-	-	1	-	-
Middle	1.26	0.98 to 1.62	0.068	1.19	0.90 to 1.57	0.225	1.09	0.78 to 1.50	0.611	0.90	0.57 to 1.43	0.662
High	0.94	0.26 to 3.36	0.919	0.72	0.15 to 3.46	0.677	2.38	0.33 to 17.02	0.387	-	-	0.999
FIB-4
Low	1	-	-	1	-	-	1	-	-	1	-	-
Middle	2.03	1.63 to 2.54	<0.001	2.78	2.14 to 3.62	<0.001	1.02	0.77 to 1.35	0.879	1.12	0.77 to 1.64	0.548
High	2.62	1.69 to 4.04	<0.001	6.39	4.05 to 10.08	<0.001	1.58	0.91 to 2.72	0.102	1.58	0.77 to 3.23	0.214
NAFLD fibrosis score
Low	1	-	-	1	-	-	1	-	-	1	-	-
Middle	1.76	0.91 to 3.40	0.096	0.98	0.46 to 2.09	0.963	1.78	0.75 to 4.24	0.190	1.44	0.45 to 4.55	0.537
High	2.03	1.01 to 4.08	0.046	2.17	1.00 to 4.67	0.049	1.74	0.71 to 4.24	0.224	1.96	0.60 to 6.42	0.264

Values in bold are statistically significant.
APRI, AST to Platelet Ratio Index; CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; FIB-4, fibrosis-4; FLI, Fatty Liver Index; HSI, Hepatic Steatosis Index; NAFLD, non-alcoholic fatty liver disease.