Studies reporting the relation between MetS and health-related quality of life (HRQoL) using SF-36 questionnaire
| Author/year | Number | Ethnicity/setting | Design | Comment |
| Scholtz et al 200727 | 1212 | Elder American men and women | Cross-sectional | Insulin resistance is associated with poor HRQoL in physical health but not in mental health. |
| Tsai et al 200814 | 361 | American obese men and women | Randomized control trial | Participants with MetS had lower HRQoL, especially at lower scores in PCS. |
| Firsman et al 200928 | 1007 | Swedish men and women | Cross-sectional | MetS associated with lower score of SF-36 in women. |
| Huang et al 201017 | 140 | Taiwanese men and women | Cross-sectional | MetS not associated with HRQoL. |
| Liu et al 201029 | 11 | Australian men and women | Prospective | Tai Chi and Qigong improved HRQoL of participants with MetS. |
| Oh et al 201030 | 52 | Korean men and women | Randomized control trial | Participants with lifestyle intervention resulted in a greater decrease in MetS than those with no intervention. |
| Zhang et al 201010 | 1785 | American men and women with coronary artery disease | Retrospective | Patients with MetS had lower score of SF-36. |
| Amiri et al 201031 | 950 | Iranian men and women | Cross-sectional | MetS associated with poor HRQoL in women. |
| Hjellset et al 201032 | 198 | Pakistani immigrant women in Norway | Cross-sectional | Women with MetS had lower scores in PCS than women without MetS. |
| Vetter et al 201115 | 390 | American obese men and women with at least one additional criteria for MetS | Cross-sectional | MetS not associated with HRQoL. |
| Katano et al 201218 | 4480 | Japanese men and women | Cross-sectional | MetS associated with poor HRQoL in men and women. |
| Tziallas et al 20125 | 359 | Greek men and women | Cross-sectional | MetS associated with lower scores in PCS and MCS of HRQoL. |
| Amiri et al 201433 | 630 | Iranian women | Cross-sectional | MetS is associated with poor HRQoL in reproductive age but not in postmenopausal women and the association mainly related to physical rather than mental health. |
| Amiri et al 201534 | 950 | Iranian men and women | Cross-sectional | MetS associated with poor PCS in women. Age and smoking are the most important sociodemographic factors affecting the gender-specific association in the MCS. |
| Jahangiry et al 201635 | 317 | Iranian men and women | Cross-sectional | People with MetS experienced lower HRQoL than without MetS. High BP and abdominal obesity are associated with lower HRQoL in participants with MetS. |
| Donini et al 201636 | 253 | Italian men and women | Cross-sectional | MetS not associated with HRQoL. |
| Hatami et al 201620 | 946 | Iranian men and women | Cross-sectional | MetS associated with poor PCS of HRQoL in women but not men. |
| Amiri et al 201837 | 950 | Iranian men and women | Cross-sectional | The association between MetS and HRQoL followed a sex-specific pattern, mainly significant only in women and in the physical aspect. |
| The current study | 2588 | Taiwanese men and women | Cross-sectional | MetS not associated with HRQoL. Hypertension and abdominal obesity are associated with lower HRQoL in participants with MetS. |
BP, bodily pain; MCS, mental component summary ; MetS, metabolic syndrome; PCS, physical component summary; SF-36, 36-Item Short-Form Health Survey.